Hepatic cholangiocarcinoma in a feline and anatomopathologic and clinical findings, compatible with Feline Infectious Peritonitis
Journal Title: Revista MVZ Cordoba - Year 2012, Vol 17, Issue 2
Abstract
Path morphological findings are presented regarding hepatic cholangiocarcinoma (CGC) with peritoneal effusion in a elderly domestic cat; its relation with clinical symptoms and pathological findings consistent with feline infectious peritonitis (FIP). The veterinary clinic of the Universidad de los Llanos dealt with a feline patient 8 years old, criollo, with increased abdominal silhouette and depression. 7% dehydration, hypothermia (37.2°C), pale mucous membranes, dyspnea and hepatomegaly were determined clinically. A performed abdominocentesis presented nonseptic exudate and a cytological symptom consistent with CGC with low columnar cells arranged in a honeycomb structure, presenting anisokaryosis, moderate hipercromacia, clear cytoplasm and accompanied by a dirty inflammatory and hemorrhagic background with cellular debris. The radiographic analysis showed hepatomegaly with a dotted pattern characteristic of neoplastic and ascite formations. A necropsy showed hemothorax and hydropericardium, ascites and white solid neoplastic nodules in 45% of the liver parenchyma and nodular pattern on the visceral surface of the stomach, small, large and mesentery intestine. Samples were placed in 10% buffered formalin, processed by routine methods for optic microscopy. In relation to histopathology moderately differentiated CGC was diagnosed with intense desmoplasia. A hepatic CGC was evidenced Cytologicly as well as histopathológicly with peritoneal effusion that was associated with clinical symptoms and anatomopathological findings consistent with FIP.
Authors and Affiliations
Julieta Ochoa A, M. Sc| Universidad de los Llanos, Facultad de Ciencias Agropecuarias y Recursos Naturales, Escuela de Medicina Veterinaria y Zootecnia, Villavicencio, Meta, Colombia.Correspondencia: julietaeochoa@yahoo.es, AI Roque, M. Sc| Universidad de los Llanos, Facultad de Ciencias Agropecuarias y Recursos Naturales, Escuela de Medicina Veterinaria y Zootecnia, Villavicencio, Meta, Colombia, JA Daza H, MVZ| Universidad de los Llanos, Facultad de Ciencias Agropecuarias y Recursos Naturales, Escuela de Medicina Veterinaria y Zootecnia, Villavicencio, Meta, Colombia
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