Hepatitis C Virus (HCV) RNA Quantification and Typing for the Identification of HCV Genotypes in clinical isolates
Journal Title: International Journal of Biomedical and Advance Research - Year 2015, Vol 6, Issue 6
Abstract
The frequency of infection with the major genotypes of hepatitis C virus (HCV) was investigated in the current study. 30 serum specimens were quantified for HCV RNA viral load and their titer values were observed with the usage of Real Time PCR in-between 1.05x101-9.58x107IU/ml. HCV genotype 3a was found in 17(56.6%) cases with highest prevalence. Genotypes 1a, 1b, 2a, 2b ,3b ,4, and 5a was found 2(6.6%),15(50%),5(16.6%),15(50%),2(6.6%),2(6.6%),2(6.6%) respectively. The findings also included that HCV viral RNA titre was elevated in HCV genotype 3a, assuming that HCV genotype 3a is the most replicated virus and need to be monitored thoroughly during diagnosis. Although type 1a, 1b, 2a, 2b, 3b, 4,5a were also present but in lower proportion.
Authors and Affiliations
Narotam Sharma, Meenakshi Bahuguna, Sneha Rawat, Neelam Panwar, Priyanka Chauhan, Rakhi Kaushik, Satish Chandra Nautiyal, R K Singh
Keywords
Related Articles
- EP ID EP204063
- DOI 10.7439/ijbar.v6i6.2108
- Views 173
- Downloads 0
Porta Hepatis in Normal Liver
Background: Hepatic surgery requires comprehensive knowledge of structures passing through porta hepatis. This fact prompted us to undertake the study of porta hepatis (PH). Our aim was to find out the dimensions, shape...
Hypolipidemic Activity of of Madhuca longifolia in Triton Induced Hyperlipidemic Rats
Objective:In the present study, an aqueous extract from Madhuca longifolia bark was evaluated for its hypocholesterolaemic and hypotriglyceridaemic activities using Triton WR-1339 induced hyperlipemic rats as experimenta...
Perception of different teaching aids by the final year MBBS students in a Medical College
Introduction: Time to time evaluation of medical curriculum by experts is the routine practice in medical education. However the students perception and opinion about the teaching - learning methodology is equally import...
Effect of cyclophosphamide on liver in albino rats: a comparative dose dependent histomorphological study
Cyclophosphamide is a commonly used anti cancer drug used in almost all regimens for treating a wide variety of carcinomas. It is a prodrug that gets activated in the liver subjecting the organ to a very high amount of t...
The rare giant cell tumor of soft tissue - An Indian perspective: Case report with review of the available Indian literature
Primary giant cell tumors of soft tissue (GCT-ST) bearing a resemblance to giant cell tumors of bone, are rare but distinct entities, first described by Salm and Sissons in 1972, closely followed by Guccion and Enzinger....