Hepatitis E outbreak in Nepal during 2014
Journal Title: JOURNAL OF ADVANCES IN BIOLOGY - Year 2014, Vol 5, Issue 2
Abstract
Hepatitis E Virus (HEV) is prevalent in developing country like Nepal. There were many sporadic cases as well outbreak is reported from Nepal. The first epidemic of hepatitis E reported in 1973 at Kathmandu, which affected more than 10,000 people, mostly young adults of the age group 25±8. The disease was associated with high incidence of acute hepatic failure and high mortality among pregnant women. There was a massive outbreak of HEV during 2014 infecting more than 6,000 individual with 11 deaths by hepatitis E in Biratnagar Municipality of Nepal within two month between April-May during 2014 outbreak. The first case of HEV documented in first week of April, 2014 and reached to pick level in last week of April. For this study, serum sample was collected from 526 patients and were subjected for the detection of immunoglobulin M (IgM) classes of antibodies against HEV by indirect (sandwich) enzyme immunoassay. Among the 526 samples, IgM anti-HEV-positive percentage from different age groups were 43.84% for ≥25-≤50, 39.71% for >50 and 32.62% for <25 years of age. Our result shows HEV infection is mostly prevalence among the intermediate age group of population. Only two pregnant women out of 526 were infected with HEV. There was no reported death among the pregnant women during 2014 outbreak.
Authors and Affiliations
Birendra Prasad Gupta, Adhikari A, Chaudhary B, Manandhar KD, Yadav SB, Shrestha N, Rauniyar R, Patel BD
Keywords
Related Articles
- EP ID EP654395
- DOI 10.24297/jab.v5i2.3767
- Views 179
- Downloads 0
P53 TRANSCRIPTION FACTOR AND DIABETES: IS THERE ANY LINK?
Diabetes, a metabolic disorder is alarmingly increasing across the globe and currently ample of research is being carried out to treat hyperglycaemia and its secondary complications in diabetic patients. Despite extensiv...
Effects of Plant Drugs on Lipid Peroxidation in Irradia ted Cells Onion Seeds
It is shown that seed treatment with herbal preparations before irradiation reduced the level of lipid peroxidation in the cells of Allium cepa.
Effect of Electroacupoint in treatment of Pain during first stage of labor
Aims: To investigate the effect of TENS on acupoints for reducing pain during first stage of labor .Study design: Experimenal.Place and Duration of study: Department of Obstetrics,Kafrelsheikh General Hospital-Kafrelshei...
Seasonal variation in the population of Black kite (Milvus migrans), inhabiting the Arid Zone of Rajasthan
The population of Black kite (Milvus migrans) inhabiting rural and urban area of Churu city, Rajasthan was seasonally determined by the direct count method. The counting of the Black kite was made at roosting sites of Ch...
Chromium combination tannage of rural and minimal tanned crusts
Chrome tanning gives the tanned hide/ skins many good properties such as degree of fullness ,softness , resilience standard shrinkage temperature . The study aims to make use of this by a ppling combination tannage. This...