Hepatoblastomas in Oman Unveiling success
Journal Title: Sultan Qaboos University Medical Journal - Year 2015, Vol 15, Issue 1
Abstract
Objectives: Primary malignant liver tumours account for more than 1% of all paediatric malignancies, with the most common form being hepatoblastomas (HB). Such malignancies among Arab populations have rarely been addressed in the literature. Using data from Oman’s sole national referral centre for childhood solid malignancies, this study aimed to present the nationwide Omani experience with HB over the past 21 years. Methods: Tis retrospective study reviewed the medical records of all children with HB who were managed in the Royal Hospital, Muscat, Oman, between January 1991 and April 2012. Clinical, radiological and laboratory characteristics were examined as well as treatments and outcomes. Results: During the study period, 15 patients with HB were treated. Of these, 10 have survived to date. Nine of the survivors were no longer receiving treatment and one patient still had the disease but was in a stable condition. Of the remaining fve patients, three did not survive and two were lost to follow-up. Te survival rate among patients who completed therapy was 91%. Conclusion: HB has an excellent prognosis in Oman. Te main obstacle to improving outcomes among Omani patients is non-compliance with therapy.
Authors and Affiliations
Fatma Rabah| Department of Child Health, Sultan Qaboos University Hospital, Nagwa El-Banna| Department of Paediatric Haemato-Oncology, Royal Hospital, Muscat, Oman, Dipali Bhuyan| Department of Paediatric Haemato-Oncology, Royal Hospital, Muscat, Oman, Ibrahim Al-Ghaithi| Department of Paediatric Haemato-Oncology, Royal Hospital, Muscat, Oman, Mohamed Al-Hinai| Department of Paediatric Haemato-Oncology, Royal Hospital, Muscat, Oman, Amal Al-Sabahi| Department of Paediatric Haemato-Oncology, Royal Hospital, Muscat, Oman, Nawal Al-Mashaikhi| Department of Paediatric Haemato-Oncology, Royal Hospital, Muscat, Oman, Ismail Beshlawi| Department of Child Health, Sultan Qaboos University Hospital
Keywords
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