HEPATOPROTECTIVE EFFECT OF INDIGOFERA LINNAEI ALI. ON CARBON TETRACHLORIDE INDUCED WISTAR ALBINO RATS
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2014, Vol 5, Issue 5
Abstract
The present investigation has been carried out the hepatoprotective activity of Indigofera linnaei Ali on carbon tetrachloride induced wistar albino rats. Carbon tetrachloride induced liver damage was well manifested by significant increase in the activities of Aspartate transaminae (AST), Alanine transaminase (ALT), Alkaline phosphatase (ALP), Gamma glutamyl transferase (GGT), Total Bilirubin, Cholesterol, Triglycerides, Lipid peroxide (LPO) also decreased the levels of Total protein, Glycogen, Superoxide dismutase (SOD) and Reduced glutathione (GSH). The oral administration of Indigofera linnaei Ali (100 mg/kg bw) along with carbon tetrachloride for 21 days reversed these altered parameters to normal level which indicating the hepatoprotective efficacy of Indigofera linnaei Ali against carbon tetrachloride induced liver injury.
Authors and Affiliations
M. Akila, G. Prasanna
Keywords
Related Articles
- EP ID EP121292
- DOI 10.7897/2230-8407.050581
- Views 85
- Downloads 0
A REVIEW ON: PREVENTIVE MAINTENANCE AND TROUBLE SHOOTING OF HPLC
In analytical world HPLC (High Performance Liquid Chromatography) is the more power full tool and it is highly automated and tremendously sensitive. HPLC equipment economically high cost also. In contrast former day’s ma...
PREVALENCE OF ANEMIA AMONG PREGNANT WOMEN IN ETHIOPIA AND ITS MANAGEMENT: A REVIEW
Anemia is a major global health problem, especially in developing countries and is a common and serious problem in pregnancy. It has serious short- and long-term consequences during pregnancy and beyond. This fundamental...
FTIR ANALYSIS FOR SCREENING VARIATION IN ANTIMICROBIAL ACTIVITY OF FRESH AND DRIED LEAF EXTRACT OF RHYNCHOSTYLIS RETUSA: A THREATENED ORCHID SPECIES OF ASSAM, NORTH EAST INDIA
This study was designed to analyze FTIR data to evaluate the role of functional groups in variation of antimicrobial potential of fresh and dried leaf extract of Rhynchostylis retusa a threatened orchid species of Assam,...
STABILITY OF CODEINE: CHARACTERIZATION OF OXIDATION PRODUCTS OF CODEINE FORMED IN AQUEOUS SOLUTION
The aim of the present study was to characterize some compounds resulting from storing codeine aqueous solutions under different conditions in search of an impurity observed in some codeine preparations and in the urine...
DUOCAP: THE CAPSULE IN CAPSULE TECHNOLOGY
In this article, the study of never technology of capsule in solid dosage form among all in pharmaceutical dosage forms. This review includes newer trends related to capsule shell, capsule fill material, capsule sealing...