Hepatoprotective efficacy of edible macrofungi Dacryopinax spathularia (Schwein) and Schizophyllum commune (Fries) against Carbon tetrachloride induced hepatotoxicity in albino Wistar rats
Journal Title: Journal of Applied and Natural Science - Year 2019, Vol 11, Issue 1
Abstract
In the present study the hepatoprotective efficacy of two edible macrofungi Dacryopinax spathularia and Schizophyllum commune has been assessed against CCl4-induced hepatotoxicity in albino wistar rats. The administration of CCl4(1ml/Kg) resulted into significant (p<0.05) rise in the levels of liver function marker enzymes Alanine Transaminase (ALT), Aspartate Aminotransferase (AST), Alkaline Phosphatase (ALP) and bilirubin and decrease in the levels of total protein and albumin in blood. On administration of low dose (250mg/Kg) and high dose (500mg/Kg) of both macrofungal extracts in different hepatotoxic group of rats, the serum levels of AST, ALT, ALP and bilirubin significantly (p<0.05) lowered down and the levels of total protein and albumin significantly (p<0.05) increased in comparison to the hepatotoxic group of rats, reflecting the hepatoprotective impact of both the extracts.
Authors and Affiliations
Amar Kumar, Manoj Kumar, M. Sinha
Keywords
Related Articles
- EP ID EP485129
- DOI 10.31018/jans.v11i1.1959
- Views 60
- Downloads 0
Preliminary checklist of moths (Lepidoptera: Glossata) of Annamalai Nagar, Tamil Nadu
The present research was carried out to document the moth fauna of Annamalai Nagar during December, 2015 to November, 2016 comprising four seasons for a period of one year, from agriculture and horticulture ecosystems us...
Character association studies in grape accessions selected from Leh district of Jammu and Kashmir
Characters association and path analysis was studied in fifty genotypically diverse grape (Vitis vinifera L.) accessions for 20 important quantitative characters. The genotypic and phenotypic association of yield was sig...
Histopathological changes in the gill architecture of Labeo rohita from the pond adjacent to thermal power station, Koradi, Nagpur, India
The hazardous effect of water pollution on the histopathology of selected organs of the freshwater fish Labeo rohita was studied with respect to thermal power plant effluent. The purpose of this research paper is to stud...
Oxidative stability and storage quality of Menthalongifolia L. extract fortified fish nuggets at refrigeration temperature
The present study was experimented to explore antioxidant potential of herb viz. M. longifolia L. inelongating the shelf life of emulsion based fish product. Since the fish meat product contain excessive amount ofprotein...
Bio-rational insecticides toxicity against Liriomyza trifolii (Burgess) damaging Cantaloupes, Cucumis melo var. cantalupensis
Field experiments were conducted for two seasons (2015-16 and 2016-17) to evaluate bio-rational insecticides against leaf miner (Liriomyza trifolii) damaging cantaloupes and it was found that among various insecticides v...