Hepatosplenomegaly in a patient with rheumatoid arthritis treated with methotrexate
Journal Title: Αρχεία Ελληνικής Ιατρικής - Year 2010, Vol 27, Issue 4
Abstract
The case is reported of a 79 year-old female with rheumatoid arthritis, receiving treatment with methotrexate, who presented with hepatomegaly, splenomegaly, leukopenia and hypergammaglobulinemia. The diagnosis of visceral leishmaniasis was established and the patient had an excellent outcome. Visceral leishmaniasis is an extremely rare theraoccurrence in patients with rheumatoid arthritis treated with methotrexate. Other than visceral leishmaniasis reports of many other opportunistic infections or complications in patients treated with methotrexate for rheumatoid arthritis were found in the literature.
Authors and Affiliations
G. KARAGIANNIDIS, M. MANTZOURANI, A. ANASTASOPOULOU
Keywords
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