Hepatotoxicity associated with dietary energy supplements: use and abuse by young athletes
Journal Title: Annals of Hepatology - Year 2012, Vol 11, Issue 4
Abstract
In recent years there has been a significant increase in the consumption of dietary energy supplements (DES) associated with the parallel advertising against obesity and favoring high physical performance. We present the case and outcome of a young patient who developed acute mixed liver injury (hepatocellularand cholestatic) after ingestion of various “over the counter” products to increase muscle mass and physical performance (NO Xplode®, creatine, L-carnitine, and Growth Factor ATN®). The diagnosis was based on the exclusion of other diseases and liver biopsy findings. The dietary supplement and herbal multivitamins industry is one with the highest growth rates in the market, with annual revenues amounting to billions and constantly lacking scientific or reproducible evidence about the efficacy and/or safety of the offered products. Furthermore, and contrary to popular belief, different forms of injury associated with these natural substances have been documented particularly in the liver, supporting the need of a more strict regulation.
Authors and Affiliations
Giovanni Avelar-Escobar, Jorge Méndez-Navarro, Nayeli Ortiz-Olvera, Guillermo Castellanos, Roberto Ramos, Víctor Gallardo-Cabrera, José de Jesús Vargas-Alemán, Óscar Díaz de León, Elda Rodríguez, Margarita Dehesa-Violante
Keywords
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