HERBOSOMES: A NEW ARENA FOR HERBAL DRUG TECHNOLOGY, A REVIEW
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2017, Vol 4, Issue 11
Abstract
The effectiveness of any herbal medicaments is dependent on the delivery of effective level of the therapeutically active compounds. Herbosomes are recently introduced the herbal formulations that have better bioavailability and actions than the conventional botanical extracts. The term “Herbo” means plant while “some” means cell like structure. Most of the biologically active components of plants are polar or water soluble molecules. However, water soluble phytoconstituents (flavonoids, tannins, glycosides) are poorly absorbed either due to their large molecular size which cannot absorb by passive diffusion or due to their poor lipid solubility, severely limiting their ability to pass across the lipid rich biological membrane resulting poor bioavailability. Herbosome technology enhances the bioavailability of herbal extracts. Herbosome act as bridge between novel delivery system and conventional delivery system. It is a complex of natural active ingredients and phospholipids (phosphatidylcholine, phosphatidylserine etc.) which increases absorption of herbal extract. Phytosome technology has been effectively used to enhance the bioavailability of many popular herbal extracts including milk thistle, ginkgo biloba, grape seed, green tea, hawthorn, ginseng etc and can be developed for various therapeutic uses or dietary supplements.
Authors and Affiliations
Chinmoy Bhuyan
Keywords
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