Hereditary Spherocytosis – A Case Report
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 2
Abstract
Hereditary spherocytosis is the most common cause of chronic hemolytic anemia. Deficiency in predominantly spectrin and also in other protein such as band 3, protein 4.2 and ankyrin is the main etiology. Clinical presentation varies from anemia, reticulocytosis, splenomegaly to symptoms and signs arising due to its complications such as chronic leg ulcers, hemolytic crisis, aplastic and megaloblastic crisis and cholelithiasis. Peripheral blood smear, reticulocyte counts, osmotic fragility studies and ultra sonography of abdomen are essential investigations for the diagnosis of hereditary spherocytosis. Milder forms of hereditary spherocytosis are asymptomatic. We present a case of a 24 year old male who presented with pain in abdomen and icterus. Investigations revealed the case to be of hereditary spherocytosis. The patient was posted for splenectomy and was on post splenectomy prophylaxis.
Authors and Affiliations
Wasim M Khatib
Keywords
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