Heroin Maintenance Treatment - Are the Further Investigation Needed?

Journal Title: Macedonian Journal of Medical Sciences (MJMS) - Year 2012, Vol 5, Issue 4

Abstract

The aim of this review is to give new emphasis to key aspects of the proposed treatment of drug addiction. Surveys for so called “second-line” treatment of drug addiction, with heroin (diacetylmorphine) as a pharmaceutical preparation, started since 1990, but this issue is becoming particularly popular in the last period. Drug addiction according to WHO and International Classification of Diseases (ICD10) is chronic, relapsing disease characterized by compulsive drug seeking and use despite harmful consequences as well as neurochemical and molecular changes in the brain. Drugs generate crime, violence and other social problems that are damaging society as a whole. Drug addiction is medical disorder to which contributes more factors and it is necessary to implement the treatment in multi disciplinary manner - from pharmacological, psychiatric, and social aspect. In recent periods studies are carrying out in several countries in the European region, to provide justification, with the scientific medical evidence, for use of heroin as a pharmaceutical dosage form, for treatment of drug addictions for previously unresponsive group. This review paper is focused on maintenance treatment with heroin, retention of the patients into treatment, whether the dose that is expected to be effective at the same time is safe, which organ (systems) are involved in eliminating the drug from the body, whether the injection is the best way for application of the drug. Purpose of this review paper is not to be supporter or opponent, but to inform, transparently to discuss all aspects and to set conclusions about this type of treatment, within national strategy context.

Authors and Affiliations

Tatjana Petrushevska| Ministry of Health of the Republic of Macedonia, Skopje, Republic of Macedonia

Keywords

Related Articles

Occupational Sharp Injuries and Biological Markers of Hepatitis B and Hepatitis C Viral Infection in Nurses

Background: Nurses are at risk for occupational exposure to blood-borne pathogens (BBP), including hepatitis B (HBV), and hepatitis C virus (HCV). Occupational exposure to BBP among nurses includes percutaneous injurie...

Neonatal Complications Related with Prolonged Rupture of Membranes

Background. Prolonged rupture of membranes (PROM) is a common and significant cause of preterm labor and has a major impact on neonatal morbidity and mortality. The aim of this study was to determine maternal risk fact...

Value of Ultrasound Machine Settings Optimization for Better Diagnosis of Focal Liver Lesions

Background. Focal liver lesions and metastasis can be very hard to localize. For best imaging, customizing of several settings of the machine are necessary: brightness, contrast, probe frequency, focusing, dynamic rang...

Efficacy of Zonisamide – Levetiracetam Comedication in Nine Adult Patients with Difficult to Treat Epilepsy and Intellectual Disability (A Case Series Report)

Aim: Few studies have concerned anticonvulsive combination therapies in epilepsies resistant to established antiepileptic drugs in monotherapy. We sought to delineate the effects of zonisamide – levetiracetam comedic...

Qualitative Histological Analysis of Adrenal Cortex Following Application of Medroxyprogesterone Acetate

Aim. The aim of the investigation was to make a review of the morphological characteristics of the adrenal cortex following the application of high doses of medroxy-progesterone acetate (MPA). Material and Methods. Tot...

Download PDF file
  • EP ID EP8896
  • DOI 10.3889/MJMS.1857-5773.2012.0238
  • Views 304
  • Downloads 14

How To Cite

Tatjana Petrushevska (2012). Heroin Maintenance Treatment - Are the Further Investigation Needed?. Macedonian Journal of Medical Sciences (MJMS), 5(4), 453-461. https://europub.co.uk/articles/-A-8896