Hidden Urinary Tract Infection in Children with Nephrotic Syndrome
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 5
Abstract
Background: Urinary Tract Infection (UTI) is a common infection in nephrotic Syndrome. Most of UTI infection are asymptomatic and remains undiagnosed. This may leads to poor steroid response, frequent relapse and long term renal damage. Methods: 50 case of nephrotic syndrome was diagnosed by clinical history and laboratory tests. Urine for Routine microscopic examination and culture –sensitivity was done in all patients. Data regarding proteinuria, pyuria and etiological organisms were analyzed by statistical method. Results: UTI was present in 30% of nephrotic children and most cases (66.6%) were asymptomatic. Mean serum albumin in nephrotic syndrome with UTI was lower than that of children without UTI (2.1 gm/dl vs. 3gm/dl, P value<0.05 ) while mean serum cholesterol in nephrotic syndrome with UTI was higher than that of children without UTI (415 mg/dl Vs 350 mg/dl, p value < 0.05). Pyuria had poor association with definite UTI (p value > 0.05). E-coli were the commonest organism followed by klebsiella. Conclusion: UTI is one of the most common infections in nephrotic syndrome and is mostly asymptomatic. It should be screened in every nephrotic child routinely to prevent long term renal damage.
Authors and Affiliations
Rakesh Ranjan Kumar
Keywords
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