High-dose and Long-term Users of Hypnotic and Sedative Drugs among Taiwanese Outpatients: Prevalence and Correlates from a Population-based Analysis

Journal Title: Journal of Advances in Medicine and Medical Research - Year 2014, Vol 4, Issue 7

Abstract

Aims: This study aims to analyze the dose and length of hypnotic and sedative drug prescriptions under a free-to-visit health insurance system. Study Design: Outpatients aged 15 years and older covered by the Taiwan National Health Insurance during 2007 (N=1,337,444) are included in this study. Methodology: The total amount of prescriptions for each patient was described according to the WHO Defined Daily Dosage (DDD) equivalent. Participants were categorized into 4 groups by dimensions of length (90 days) and dose (3 DDD per day). Patient characteristics and prescription drug use patterns were examined using a multinomial logit regression. Results: Although most prescription doses fell within the recommended ranges, the average flunitrazepam dose was substantially higher than that recommended for both long-term and high-dose users. Our results indicate that male sex, a psychiatric illness diagnosis, and receiving care at more than one institute were positively correlated with long-term use. However, these factors were negatively correlated with high-dose user. Distinct differences between the characteristics associated with long-term and high-dose use were observed, compared with normal users. Conclusion: These findings call for clinicians and policy makers to focus their attention on potential safety and efficiency issues. The alignment of prescribing practices and guidelines is highly recommended.

Authors and Affiliations

Yu-Ping Wen, Ming-Ju Shieh, Hui-Chin Lin, Hsu-Min Tseng

Keywords

Related Articles

The Association between Knee Osteoarthritis and Changes in the Achilles Tendon: A Cross-sectional Study

Aim: To explore the association between knee osteoarthritis (OA) and morphological changes in the Achilles tendon. Study Design: Pilot cross-sectional study. Place and Duration of the Study: Rheumatology Unit, Barzilai M...

Case Reports of Neuroinvasive Manifestation of Viral Encephalitis

West Nile virus (WNV) infection is a mosquito-borne viral disease, which can cause an inflammation of the brain and meningitis. WNV is commonly found in Africa, West Asia, the Middle East and Europe. For the first time i...

Revitalization of a Geminated Tooth with a Necrotic Pulp and an Open Apex Using Platelet–Rich Plasma (PRP) and Mineral Trioxide Aggregate (MTA): A Case Report

Aim: To successfully revascularize a geminated maxillary lateral incisor with an open apex using platelet-rich plasma (PRP) and mineral trioxide aggregate (MTA). Methods: A 21-year-old male was referred for endodontic t...

Atosiban– Its Impact on Uterine Activity in Preterm Labour

Aims: To study the effect of Atosiban on Uterine activity using tocodynamometer and to evaluate the extent to which the delivery was delayed with the administration of oxytocin receptor antagonist. Study Design: Open lab...

Prevalence and Clinical Pattern of Acute and Chronic Complications in African Diabetic Patients

Aims: The aim of this study was to describe the proportion, pro¬file and clinical pattern of acute and chronic complications associated with diabetes and its potential risk factors. Study Design: This was a retrospective...

Download PDF file
  • EP ID EP349003
  • DOI 10.9734/BJMMR/2014/7188
  • Views 58
  • Downloads 0

How To Cite

Yu-Ping Wen, Ming-Ju Shieh, Hui-Chin Lin, Hsu-Min Tseng (2014). High-dose and Long-term Users of Hypnotic and Sedative Drugs among Taiwanese Outpatients: Prevalence and Correlates from a Population-based Analysis. Journal of Advances in Medicine and Medical Research, 4(7), 1577-1590. https://europub.co.uk/articles/-A-349003