HIGH SENSITIVE C-REACTIVE PROTEIN AND ITS RELATIONSHIP WITH OTHER CARDIOVASCULAR RISK VARIABLES IN OBESE, OVERWEIGHT AND HEALTHY INDIVIDUALS
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2018, Vol 11, Issue 8
Abstract
Objective: More than 50% of the world’s population is considered overweight and being overweight is associated with several comorbidities such as Type 2 diabetes mellitus, hypertension, cardiovascular diseases, dyslipidemia, respiratory diseases, osteoarthritis, and depression. Therefore, in this study, we have estimated the high sensitive C-reactive protein (hs-CRP) levels in obese, overweight, and normal body mass index (BMI) individuals and whether there was any relationship between hs-CRP and other risk factors of the cardiovascular system such as serum total cholesterol (TC) and other lipids.Methods: A total of 150 participants, divided into three groups. Group I - 50 participants with normal BMI (18–22.99 kg/m2), Group II - 50 participants who were overweight (BMI = 23–24.99 kg/m2), and Group III - 50 who were obese (BMI ≥25 kg). We measured fasting plasma glucose, postprandial plasma glucose, serum TC, triacylglycerol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and hs-CRP.Results: Obese individuals had increased hs-CRP compared with control (Group I) and overweight (Group II) groups. hs-CRP positively correlated with BMI and lipid profile.Conclusion: Elevated hs-CRP was associated with cardiovascular risk factors in overweight and obese individuals. This high-risk group should be targeted for therapeutic lifestyle modifications to prevent further complications.
Authors and Affiliations
Gayathri B, Vinodhini Vm
Keywords
Related Articles
- EP ID EP567336
- DOI 10.22159/ajpcr.2018.v11i8.26056
- Views 95
- Downloads 0
ACACIA SENEGAL BARK EXTRACT IN REGULATION OF HYPOTHYROIDISM: AN EXPERIMENTAL APPROACH
Objective: The objective of the present study was to evaluate the thyroid hormone stimulating efficacy of Acacia senegal (Gum Arabic) bark extract in 6-n-propyl-2-thiouracil (PTU)-induced hypothyroid albino rats.Methods:...
NEUROPROTECTIVE EFFECTS OF AQUEOUS EXTRACT OF HYDROCOTYLE JAVANICA IN AMELIORATING NEUROBEHAVIORAL ALTERATION INDUCED BY MERCURY
Objective: This study aims to assess the effects of the aqueous extract of Hydrocotyle javanica (HJ) in ameliorating mercury-induced neurobehavioral toxicity.Methods: For the study, 36 adult male Swiss albino mice of 25â...
EVALUATION OF IN VITRO INHIBITION OF PROTON􀇧PUMP BY NANOSILVER PARTICLES SYNTHESIZED USING SEEDS OF ANETHUM GRAVEOLENS
Objective: The green synthesis of nanoparticles is gaining popularity owing to its several advantages over the chemical methods. This study reports the biosynthesis of nanosilver mediated by the extract of the seeds of A...
A STUDY ON PHYTOCHEMICALS, ANTIMICROBIAL, AND SYNERGISTIC ANTIMICROBIAL ACTIVITIES OF HIBISCUS SABDARIFFA
Objective: The aim of the present study was to screen phytochemical constituents and evaluate antimicrobial and synergistic antimicrobial properties of leaves and stem of Hibiscus sabdariffa. Methods: The extraction wa...
DEVELOPMENT OF POLYHERBAL WITH ANTIOXIDANT ACTIVITY
Objective: The objective of this research was to develop a polyherbal formulation (PHF) using four different herbs and to evaluate their phytochemicals, physical constants, and determination of their antioxidant activity...