High sensitive C- reactive protein in acute ischemic stroke and its short term Prognostic significance: A study from rural hospital.
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 9
Abstract
Abstract: Stroke is the third leading cause of death in developed countries. Ischemic brainInjury is characterized by acute local inflammation and changes in levels of inflammatory cytokines, notably C reactive protein.High sensitivity C reactive protein can predict recurrent cardiovascular disease, stroke and death in different settings. There is lack of studies on high sensitive C reactive protein in acute ischemic stroke patients from rural area in our nation. The objective of the study was to measure high sensitivity C reactive protein levels in acute ischemic stroke and to assess short term prognosis in terms of mortality and morbidity with reference to high sensitivity C reactive protein levels during one week of hospital stay. It was a longitudinal study involving 50 patients admitted with acute ischemic stroke in medicine department. Routine investigations, high sensitivity C reactive protein levels and computed tomography scan of brain were done in all these patients. High levels of high sensitivity C reactive protein at admission showed high mortality and morbidity during one week of hospital stay. High levels of high sensitivity C reactive protein correlated with poor functional outcome using Barthel index. Thus quantitative estimation of high sensitivity C is reactive protein a simple test and helps in predicting prognosis. Keywords: Acute ischemic stroke, Barthel Index, Cerebrovascular disease, Dyslipidemia, Hypertension, High sensitivity C-reactive protein
Authors and Affiliations
Madhura Talkad Lakshmikumar, Shruthi Bettegowda, Addepalli Yamini
Keywords
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