HIGH SENSITIVITY C - REACTIVE PROTEIN AS A PROGNOSTIC MARKER IN ACUTE STROKE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2014, Vol 3, Issue 10
Abstract
[b]OBJECTIVES:[/b] To determine raised serum hsCRP levels, an established risk marker in stroke patients and also to study the co relation between raised serum uric acid and hsCRP levels in ischemic and hemorrhagic stroke. [b]MATERIALS AND METHODS[/b]: This was a cross sectional study of 200 patients presenting with a history of focal neurological deficit of acute onset in the form of hemiparesis, hemiplegia having evidence of presence of ischemic or hemorrhagic infarct in CT scan of brain. In all patients hsCRP levels were measured within 48hours of presentation. [b]RESULTS[/b]: Most of the patients (65%) were in the age group of more than 50 years. Left-sided hemiparesis with altered sensorium and UMN facial palsy was the most common presenting symptom. hsCRP levels were found to be increased in hemorrhagic stroke patients than with ischemic stroke, this difference was found to be statistically significant (p < 0.001). [b]CONCLUSION: [/b]From this study we concluded that hsCRP level is increased in cases of stroke - ischemic as well as hemorrhagic, but more in hemorrhagic stroke suggesting an inflammatory response in acute stroke. Furthermore, the increased levels correlated with larger bleed and infarct size, severe neurological deficit and worse outcome.
Authors and Affiliations
Jayachandra , Mamatha T. R, Veeranna Gowda, Sowrabha Bhat, Raghavendra , Yashavanth Gangadkar
Keywords
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- EP ID EP127834
- DOI 10.14260/jemds/2014/2191
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