High-sensitivity C-Reactive Protein concentration in Patients with Acute Coronary Syndrome of Central India
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 4
Abstract
Background and Objectives: Atherosclerosis is now known to be an active process of cell activation, inflammation and thrombosis.1 To study, the serum hs- CRP level, a biomarker of inflammation in patients with acute coronary syndrome, such studies are sparse in India. Methods: Patients with ACS who were fulfilling the inclusion criteria, attending cardiology services of Choithram Hospital and Research Centre (CHRC), Indore (a teaching hospital), were enrolled prospectively in the study during the period February 2017 to February 2018. The patients were further classified three risk groups according to serum hs-CRP levels. < 1 mg/L - low risk, 1-3 mg/L - average risk and >3 mg/L- high risk. Results: In our study, majority of the patients were having serum hs-CRP level >3mg/l putting them in high risk category. Of 100 patients, 60 patients (60%) had serum hs-CRP level > 3mg/l, 33 patients (33%) were having serum hs-CRP level 1-3mg/l, while only 7 patients (7%) had serum hs-CRP level < 1. The mean value of the serum hs-CRP levels in our study were 4.18±3.30 mg/L. In patients with unstable angina serum hs-CRP was 2.43±1.67 mg/l, with NSTEMI it was 3.70±2.09 mg/l and with STEMI it was highest 5.41±3.83 mg/l, Conclusion: In our study we showed, the mean value of the serum hs-CRP levels in Indian subjects were 4.18±3.30 mg/L, which is higher to those reported in other ethnic groups.
Authors and Affiliations
Dr Priyanka Kiyawat
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