Histogenesis of Lung in human fetuses at different weeks of gestation in eastern India
Journal Title: International Journal of Medical and Health Research - Year 2018, Vol 4, Issue 7
Abstract
Histogenesis of Lung was studied using 40 normal human fetuses ranging from 8 to 26 weeks of gestation, under Light Microscopy after sectioning the lung and staining with Haematoxylin and Eosin. The Bronchial buds undergo repeated division to form bronchial tubes that differentiate into different parts of intrapulmonary bronchial tree. In earlier weeks of Gestation Mesenchymal tissue are more. Developing Duct lined by Cubical Epithelium, Acini and Blood vessels are visible. Developing Bronchus lined with Pseudo stratified columnar ciliated epithelium surrounded by hyaline cartilage. In High Power Bronchus surrounded by hyaline variety of cartilage which extend into lobar and segmented bronchus. But cartilage actually appear in 4th Week. Terminal bronchiole is developing with acini packed with cells are seen. In high power bronchus is thick walled and bronchiole is thin walled lined by epithelium. Multiple acini packed with cells are seen. Ducts were having tubular lumen. Welldeveloped hyaline variety of cartilage surrounded by pieces of bronchus. Bronchiole was visible. Acini are packed with cells. In later weeks of Gestation Bronchus with cartilage on High power. Bronchioles and acini are visible. Mucosal glands are developed on bronchial wall. Bronchioles were having simple columnar non-ciliated epithelium infolding. Mucosal glands were developed on wall of bronchiole. Bronchiole and Bronchi are in between well-developed septae and blood vessels were seen to be developing. Lymphatic element normally developed. Bronchioles were having low columnar to cuboidal epithelium. Serous acini was increased. Respiratory bronchiole and alveoli were increased. Each terminal bronchi were dividing into respiratory bronchiole which were seen to be dividing into alveoli.
Authors and Affiliations
Sanjukta Sahoo, Arpan Haldar, Manisha R Gaikwad, Sanjay Giri
Keywords
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