Histopathologic spectrum of adrenal lesions
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 3
Abstract
Introduction The bipartite adrenal gland has tumors arising from cortex medulla or as metastasis from extraadrenal sites Distinguishing benign from malignant types is a challenging task for pathologists this study gives an insight into adrenal lesions with their histopathological and immunohistochemical findings and its role in categorizing these tumors to aid in their diagnosis and proper managementAim To study the Histopathological patterns of adrenal lesions with clinical correlationMaterials and Methods In a five year period10 surgical specimens of adrenal tumors were resected and studied between July 2010 to June 2015 at Kamineni Institute of Medical Sciences Narketpally and King Koti Tissues were processed and stained sections were studied for histopathological patterns and IHC markers used were vimentin synaptophysin NSE chromogranin immunohistochemistry was done wherever necessary and the markers used were vimentin synaptophysin NSE chromograninResult Out of ten adrenal lesions we have studied two cases were adrenal cysts1 three were cortical adenoma one case is Adrenocortical carcinomapositive for synaptophysin vimentin two cases were neuroblastomapositive for NSE chromogranin and synaptophysin and two cases are pheochromocytoma positive for chromograninConclusion Pathological evaluation and immunohistochemical profiling has got important role in categorizing adrenal tumors along with clinical radio logical and biochemical inputs and their subsequent managementKeywords Adrenal cyst Adrenal adenoma and Carcinoma Weiss system Neuroblastoma Pheochromocytoma
Authors and Affiliations
Saritha Karre, Amrutha Gorva, Chandrakumar Shanmugam, V. D. Praveen Kumar Gorrela, Satyanarayana Vee
Keywords
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- EP ID EP475933
- DOI 10.18231/2394-6792.2018.0090
- Views 55
- Downloads 0
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