Histopathological Analysis of Lesion of Nasal Cavity, Paranasal Sinus and Nasopharynx- A Clinical Study
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2017, Vol 5, Issue 11
Abstract
Background: A variety of non-neoplastic and neoplastic lesions in the nasal cavity, paranasal sinuses and nasopharynx are commonly seen. Polypoidal mass in the nose is a very common lesion encountered in clinical practice. The present study was conducted to histopathological pattern of masses of nasal cavity, paranasal sinus and nasopharynx. Materials & Methods: It included 115 specimens of both gender of nasal cavity, paranasal sinus and nasopharynx received in the department. All the specimens were fixed in 10% formal–saline, then processed into paraffin embedded sections and stained with hematoxylin and eosin. Results: Out of 115 patients, males were 60 and females were 55. The difference was non- significant (P-1). Off 115 pathologies, 62 were non- neoplastic and 53 were neo- plastic. Most common was seen in age group 51-60 years (30) followed by 41-50 years (25), 61-70 years (14) and 21-30 years (13). Benign lesions were 22 and malignant were 31. The difference was non- significant (P>0.05). following masses were found, inflammatory polyp (62), allergic polyp (13), tuberculous granulamotous lesion (5), sinonasal papilloma (12), hemangioma (3), angiofibroma (4), undifferentiated carcinoma (2), squamous cell carcinoma (5), hemangiomapericytoma tumour (2), olfactory neuroblastoma (4) and non- hodgkin lymphoma (3). Inflammatory polyp was seen in the most. The difference was significant (P<0.05). Conclusion: Histopathological examination is simple, reliable and cost effective diagnostic procedure for the detection of various lesions of nasal cavity, nasopharynx and paranasal sinuses. Most commonly occurring lesion was inflammatory polyp
Authors and Affiliations
Anil Kumar, Neha Sood, Rashmi Gautam, Shachi Ahlawat, Kriti Nausaran
Keywords
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