Histopathological Characteristics of Central Nervous System Tumors in a Single Moroccan Center
Journal Title: Saudi Journal of Medical and Pharmaceutical Sciences - Year 2017, Vol 3, Issue 12
Abstract
Abstract:Tumors of the central nervous system represent a heterogeneous group of tumors with a varied histopathologic spectrum and a variable frequency. In this study, we retrospectively analysed the epidemiological and the histopathological data of central nervous system tumors collected in our department.This study includes 657 central nervous system tumors histologically diagnosed from 2004 to 2016. It concerns all CNS tumors according to the WHO classification. The characteristics of patients, including age, sex, location, and histologic diagnosis were analyzed. Tumors were equally seen in males and females (sex-ratio=0.99:1). The mean age at the time of diagnosis was 38 years. 24% were children and teenagers. The commonest location was intracranial (92.3%). The primary tumors accounted for 92.8% of CNS tumors. Tumors were benign in 53.5% and malignant in 46.5% of cases. The most common histologic type is astrocytic tumors (30%), followed by meningeal tumors (26.7%). In adults, the three commonest categories were meningothelial tumors, astrocytic tumors and oligodendroglial tumors.For children and teenagers, astrocytic tumors were the most prevalent, followed by embryonal tumors and ependymal tumors.There was a male predominance for astrocytic, ependymal and oligodendroglial tumors and medulloblastomas. In contrast, meningiomas and schwannomas were more frequent in female.The most frequentintracranial tumors were astrocytic tumors, meningeal tumors and embryonal tumors. In spinal cord, meningeal tumors, schwannoma and ependymal tumors were the most prevalent. In the absence of a national register of CNS tumors in Morocco, we performed this study which may reflect epidemiological and histopathological characteristics of these tumors in our region. Globally, our results were in accordance with those of other studies around the world. However, we noted a higher proportion of tumors in children and teenagers. Keywords:Central nervous system tumors; epidemiology; histopathology.
Authors and Affiliations
Nawal Hammas, Asmae Mazti, Mustapha Maaroufi, Elfaiz Mohamed Chaoui, Samira Elfakir, Laila Chbani, Hind El Fatemi
Keywords
Related Articles
- EP ID EP391760
- DOI -
- Views 79
- Downloads 0
In Vitro Antimicrobial Efficacy of Individual and Combined Extracts Of Five Medicinal Plants, Enantia chlorantha, Echinacea angustifolia, Acalypha indica, Alchemilla vulgaris, and Vernonia guineensis on Strains of Salmonella typhi
Traditional medicine is the oldest form of health care system that has stood the test of time. The African continent holds an enormous resource in terms of floral biodiversity and its medicinal plants have remained a m...
Study of StavudineMultiparticulate Floating Drug Delivery System Prepared by Emulsion Gelation Technique
Abstract: Gastroretentive systems can remain in the gastric region for several hours and hence significantly prolong the gastric residence time of drugs. Prolonged gastric retention improves bioavailability, reduces drug...
Isolation, Identification and Antimicrobial Sensitivity Pattern of Bacterial Isolates from Tracheal Aspirate of ICU Patients of Tertiary Care Hospital In Western, Rajasthan, India
Abstract:To analyze the aerobic bacteria isolated from endotracheal secretions of ventilated patients and to evaluate the antibiotic sensitivity pattern and Multi drug resistance of those isolates, present study was cond...
Assessment of Colocasiaesculenta Mucilage as Suspending Agent in Paracetamol Suspension
Abstract: The purpose of this study is to search for more affordable as well as effective natural excipients that can be used as viable alternative for the formulation of pharmaceutical suspension. The suspending propert...
Etching Gels
Aim of this work was to compare properties of two etching gels produce by Kerr Orange and Spofa Dental. Etching gel are water solution of phosphoric acid using in total etch techniques. They are applicable on enamel surf...