Histopathological evaluation of cerebral lesions
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 1
Abstract
Introduction A cerebral lesion refers to any type of abnormal tissue found in the brain particularly in the cerebral cortex The cerebrum is responsible for allowing voluntary movements within the human body Cerebral tumors arise from tissue throughout the brain Neuroglial cells mainly consist of astrocytes oligodendrocytes and ependymal cells These cells provide shelter and maintenance for neurons About half of the primary CNS tumors derive from glial cellsAims and Objectives To study the lesions of cerebrum with age and sex incidence and to find the incidence between neoplastic and nonneoplastic lesions and correlation with radiological appearance and histopathological findings of the lesionsMaterials and Methods A present study including of 150 cases of cerebral lesions All surgical biopsies were taken at department of Neurosurgery and then send for the histopathology examination in department of Pathology of Smt NHL Municipal Medical College attached with Sheth VS General Hospital Ahmedabad Gujarat from July 2011 to June 2013Results Out of these total 150 biopsies 100 were diagnosed as neoplastic lesions and 50 were diagnosed as nonneoplastic lesions Among the neoplastic lesions majority cases were of Gliomas 82 Among the nonneoplastic lesions majority cases were of infectious origin 60 Out of total 82 cases of gliomas 64 were of astrocytic Gliomas 78 The peak age incidence for patients with neoplastic lesions was the 4th and 5th decade while that for benign lesions was 1st and 3rd decade The male to female ratio was 271Summary and Conclusion Among the 100 neoplastic lesions most common was Gliomas Among the glioma most common was the Astrocytoma 78 which was followed by the oligodendroglioma 11 and then Ependymoma 6 Overall male female ratio was 271 in the patient with Glial tumors Out of 50 non neoplastic cerebral lesions 30 60 were of infectious originKeywords Astrocytoma Cerebral lesions Glioma Histopathology examination
Authors and Affiliations
Minesh B. Gandhi, Harshid L. Patel, Aakash Shah
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