Histopathological pattern of neoplastic ovarian lesions
Journal Title: International Archives of Integrated Medicine - Year 2016, Vol 3, Issue 1
Abstract
Introduction: Ovarian neoplasm is the most fascinating tumor of women in terms of its histogenesis, clinical behavior and malignant potential. The ovary is the third most common site of primary malignancy in female genital tract after cervix and endometrium accounting for 30% of all cancers of female genital tract. Aim and objectives: To study frequency and distribution of different histological types of ovarian tumors and to analyse age distribution of these tumors and to find out frequency of benign and malignant neoplasms of ovary. Material and methods: The present study was based on histopathological evaluation of 97 cases of ovarian neoplastic lesions received at the Department of Histopathology, B.J. Medical College, Ahmedabad during October 2012 to October 2013. The gross specimens received were fixed in 10 percent formalin for 24 hours and multiple sections from each specimen were taken to include the representative area for histological examination. Sections were processed by routine paraffin method, blocks were cut at five micron thickness and the sections were stained with conventional Haematoxylin and Eosin (H&E) stain. The lesions were then classified and studied according to WHO Classification of ovarian tumors. (ICD - 9th edition). Results: A total number of 97 cases were studied. Among these, 82 cases (84.5%) were benign, 2 cases (2.1%) were borderline and 13 cases (13.4%) were malignant tumors. Benign neoplasms were most commonly seen in 3rd to 5th decade, whereas malignant neoplasms were commonly seen in 5th decade. Serous cystadenoma (52.7%) was the commonest benign tumor followed by Mucinous cystadenoma (28.4%). Among the malignant surface epithelial tumors, serous cystadenocarcinomas (8.1%) were most common followed by Mucinous cystadenocarcinomas (4.1%). Conclusion: Benign ovarian tumors were more common than malignant ones for all age groups. Surface epithelial tumors were the most common class of tumors. Serous cystadenoma was the most common ovarian tumor overall as well as the most common benign tumor, whereas serous cystadenocarcinoma was the most common ovarian malignancy. Malignant ovarian tumors were more common above 40 years.
Authors and Affiliations
Dimpal Modi, Gunvanti B. Rathod, K. N. Delwadia, H. M. Goswami
Keywords
Related Articles
- EP ID EP417571
- DOI -
- Views 115
- Downloads 0
Radiological measurement of bone density to assess the efficiency of bone graft
Introduction: The ideal bone graft substitute should provide osteogenetic cells to facilitate bone regeneration, osteoinductive factors to induce bone formation and an osteoconductive matrix to directly stimulate bone de...
Influence of various psychological correlates in cardiovascular disease patients
Background: Cardiovascular disorders continue to be one of the major causes of death in the world. The central nervous system serves as a bridge for the transition; and it links psychological factors to cardiac dysfuncti...
Single dose oral gabapentin as a pre-emptive analgesic for post-operative pain relief in patients undergoing tonsillectomy
Introduction: Post-operative pain and swallowing difficulty following tonsillectomy remain one of the most difficult pain states to manage in Otolaryngology. Many therapeutic modalities - ranging from non-steroidal anti-...
Prevalence of acute on chronic liver failure, underlying etiology and precipitating factors
Background: Acute on chronic liver failure (ACLF) was first described in 1995 as a clinical syndrome distinct to classic acute decompensation. Characterized by complications of decompensation, ACLF occurs on a background...
Comparison of Friedewald’s and Anandaraja’s formula with direct estimation of low-density lipoprotein cholesterol in Shivamogga population
Background: Estimation of low density lipoprotein cholesterol (LDL-C) is crucial in management of coronary artery disease patients. There are many homogenous assays currently available for the estimation of serum LDL-C....