Histopathological Spectrum of Bronchial Biopsies in a Teaching Hospital from Kashmir Valley
Journal Title: International Journal of Medical and Health Sciences - Year 2016, Vol 5, Issue 2
Abstract
Introduction: The diagnostic yield of bronchoscopy has been assessed from different specimens obtained during procedure. The bronchial biopsy besides providing histological diagnosis renders material for other investigations like immunohistochemistry and genetic mutation studies. This study was carried out to assess the diagnostic yield of bronchoscopy exclusively from bronchial biopsies. Material and methods: A retrospective study was conducted from Dec 2014 to Nov 2015. All the bronchial biopsies received during this period were reviewed and age and gender of each case was recorded from medical records. Malignant lesions were classified according to WHO classification and Non-Neoplastic lesions were classified into four subgroups: normal histology, nonspecific chronic inflammation, chronic granulomatous inflammation and other infective lesions. Results: There were total of 181 cases. The mean age was 72.27 years and male to female ratio was 2.54:1. The histological diagnosis of malignancy was reported in 49.17 % cases, 40.88% cases had Non-Neoplastic lesions and 9.9% cases had normal histology. Conclusion: Bronchial biopsies help in diagnosing Non-neoplastic lesions as well as establishing the cell type of malignant lung lesions. The study showed that lung carcinoma has male predominance with mean age of 60.13 years. Squamous cell carcinoma is most common histological type in males and adenocarcinoma is common in females.
Authors and Affiliations
Lateef Ahmed Wani, Bushra Rashid Sahaf, Nazia Qayoom, Nusrat Ali, Shaista Mushtaq, Rukhsana Akhter, Ruby Reshi
Keywords
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