Histopathological Spectrum of Colonoscopic Biopsies: A three years study from Central India Gargi Tignath1, Akanksha Jain2
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 7
Abstract
Background: Colonoscopy is performed by passing a flexible colonoscope through the anal canal into the rectum and colon. The cecum is reached in >95% of cases, and the terminal ileum can often be examined. Colonoscopy is the gold standard for diagnosis of colonic mucosal disease. Both macroscopic and microscopic appearance along with clinical correlation helps in definitive diagnosis of the lesion, which helps in early treatment and better outcome of the patient. Aim of our study was to assess the histopathological spectrum of colonoscopic biopsies received in last three years of a tertiary care centre of central India. Materials & Methods: The present study included colonoscopic biopsies taken from colon and rectum, received in the Department of Pathology irrespective of patient’s age. Results: Out of a total 200 cases, 70 were non-neoplastic and 130 were neoplastic. In our study we observed that neoplastic lesions predominated over non-neoplastic lesions. Of 130 neoplastic lesions, 30 were benign and 100 were malignant. Malignant lesions were more in number than the benign lesions in our study. Conclusion: The histomorphological profile of colorectal biopsies has a wide spectrum, ranging from infectious conditions, inflammatory disorders, precancerous lesions to colorectal malignancies. Inflammatory pathologies are found to affect the colorectal region most frequently. Therefore colorectal lesions need an accurate diagnostic approach, wherein interpretation of colorectal mucosal biopsies by histopathologists has now taken a cornerstone place in the workup and management of patients with colorectal lesions.
Authors and Affiliations
Dr. Akanksha Jain
Keywords
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