Histopathological Spectrum of Skin Biopsies: A One Year Retrospective Study
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2017, Vol 6, Issue 4
Abstract
Introduction: Skin is involved in a number of pathological conditions and affects all age groups and both the sexes, ranging from mild to severe skin problems such as dry skin,wrinkling ,disfigurement ,itching, painful and sometimes fatal life threatening conditions like toxic epidermal necrolysis and malignancies like lymphoma. Skin biopsy is one of the most frequently used ancillary aids to confirm clinical diagnosis.The tissue reaction pattern and pattern of inflammation aid in the diagnosis. Objective: The purpose of the present study was to evaluate the skin biopsies in relation to age and sex and the pattern of histological diagnosis of skin biopsy specimens in the department of histopathology in our centre. Materials and Methods: The present retrospective study of skin biopsies was conducted in the department of histopathology of Sampurna Sodani diagnostic clinic over a period of one year from January to December 2016.A total of 173 skin biopsies were taken into consideration. All biopsies were fixed in 10% formalin for 24 hours and later 3-4 micron thick sections were made from the blocks and stained with H and E stain. Wherever necessary, PAS and AFB staining and immunohistochemistry was performed to aid in the diagnosis. Results: A total of 173 skin biopsy specimens were received from January 2016 to December 2016 . There were 76 (43.9%) males and 97 (56.1%) females. Leg was the most common site involved. Non-malignant lesions were more common comprising of 110/173 (65.3%). Borderline tuberculoid Leprosy was the most common finding among the granulomatous skin lesions (38.8%)Among the malignancies,Basal cell carcinoma was the most frequent finding (29.6%). Conclusion: Skin diseases present with a variety of patterns and severity. A definite histopathological diagnosis along with clinical presentation is mandatory for proper treatment and prognosis of the disease.
Authors and Affiliations
Ranjana Hawaldar
Keywords
Related Articles
- EP ID EP471121
- DOI 10.21088/ijprp.2278.148X.6417.23
- Views 60
- Downloads 0
Clinicopathological Study of Tuberculous Lesions of Small and Large Intestine (Including Appendix
Background: Tuberculosis in India continues to be a major health problem with approximately one eight of total cases being extra pulmonary. The gastrointestinal tract is involved in 66-75% of cases of abdominal tuberculo...
Post Transplant Liver Biopsies: A Clinicopathological Study from South India
Introduction: The spectrum of diseases encountered in post-transplant liver biopsies is broad. The pathologist plays an important role in defining these process. Aim: The aim of this study was to evaluate liver allogra...
Pattern of Leukemia in the Multi-Ethnic and Racial Population: A Hospital Based Study
Background: The purpose of this study was to analyze the trends in the incidence rates of major types of leukemia viz. acute myelogenous leukemia (AML), acute lymphocytic leukemia (ALL), chronic myelogenous leukemia (CML...
Adenomyoepithelioma of Breast in an Adolescent Girl: A Rare Clinical Presentation
The growing awareness of female breast cancer has led to increased sensitivity toward pAathological breast conditions in pediatric patients. Palpable breast masses arising in adolescent and pubertal girls are uncommon. T...
Histopathological Spectrum of Prostatic Lesions with Special Emphasis on Mimickers of Malignancy
Introduction: Blood transfusion saves millions of life around the world. However knowledge regarding the same in the young and healthy population is not adequate. Aims and Objectives: To study the knowledge, attitude and...