Histopathological Spectrum of Vesiculobullous Lesions of the Skin: Study at a Tertiary Care Hospital
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 4
Abstract
Background: Vesiculobullous lesions are one of the predominant groups of skin lesions. They are the primary morphological patterns of skin reaction to various external and internal pathologic stimuli. Various types of pathologic processes can lead to development of vesiculobullous eruptions over body. Methodology: This observational study was conducted in Department of pathology and department of dermatology. 72 patients who presented with vesiculo bullous lesions of skin not related to infectious aetiology were enrolled for the study. Clinical details and histopathological findings were analyzed. Results: Pemphigus group of disease comprised the major proportion comprising 38 cases (52.9%), out of which 31 cases were pemphigus vulgaris (43.1%), 4 cases were pemphigus foliaceus (5.6%) and 3 cases were pemphigus vegetans (4.2%). Bullous pemphigoid was the second most common type and was found in 10 biopsies (13.9%). Conclusion: Punch biopsy of the skin is a simple, inexpensive, safe OPD procedure, causing minimal discomfort to the patient. Histopathological features are conclusive in majority of vesiculobullous lesions of skin; thus it forms the primary diagnostic modality in the management of such patients where the facility for immunoflourescence technique is not available.
Authors and Affiliations
Ashutosh Kumar, Ankita Mittal, Rashmi Chauhan, Faiyaz Ahmad, Seema Awasthi, S. Dutta
Keywords
Related Articles
- EP ID EP535494
- DOI 10.21276/ijmrp.2018.4.4.058
- Views 76
- Downloads 0
Evaluation of Transfusion Practices in a Blood Bank at a Tertiary Care Teaching Centre
Introduction: The transfusion requirements for patients undergoing surgical procedures are often overestimated. The consequence of such a practice include increased cost to the patient, outdating of blood, overburdening...
Generalized Epidermolysis Bullosa Simplex, Dowling Meara in Saudi Family, Case Report and Review of Literature, Saudi Arabia 2017-2018
A 4 years old Saudi girl, her neonatal period was characterized, since first 2 days of life by nails dysplasia and yellow pigmentation then progress to well demarcated, Serous and hemorrhagic, vary in size blisters. That...
Factors Affecting Adherence of Hemodialysis Patients to Treatment in Makkah, Saudi Arabia
Background: Adherence of hemodialysis patients to medical instructions is considered crucial for a longer life expectancy and better quality of life. Despite of its importance, there is remarkable paucity in researches w...
Knowledge and Attitude of Parents toward Their Son's Circumcision at King Saud Hospital in Unaizah City: Cross-Sectional Study
Introduction: The male circumcision is a vastly applied surgery around the world with 37-39% of men being circumcised. Surgically it comprises of the removal of part or the entire foreskin (prepuce) from the penis. Compl...
A Study of Patients with Liver Cirrhosis and Portal Hypertension with Special Reference to Hematological Profile
Background: Liver cirrhosis is known to lead portal hypertension and its complications thereby. Bleeding from esophageal varices is a common cause for increased morbidity and mortality in cirrhotic patients. Early detect...