HISTOPATHOLOGICAL STUDY OF DIFFERENT FORMS OF PORIASIS AND THEIR CLINICAL CORRELATION
Journal Title: INTERNATIONAL JOURNAL OF RESEARCH IN PATHOLOGY AND MICROBIOLOGY - Year 2018, Vol 2, Issue 3
Abstract
Background Psoriasis (Gk. psora, the itch) is a chronic papulosquamous disease of unknown aetiology with unpredictable course of remission and exacerbation. Because the clinical presentation of psoriasis is varied, many times the definitive diagnosis depends on the histological examination. However both genetic and environmental factors are thought to play a role in initiation and progression of disease. Objective To correlate Clinical and Histological features of Psoriasis. Material and Methods Ÿ A total of 110 cases were studied. Clinical study will be done in Department of Dermatology, S. N. Medical College. Ÿ Histopathological study of Skin Biopsy specimens will be done in Department of Pathology, S.N. Medical College. Ÿ H & E Stained slides were studied of the cases studied. Ÿ Following Histological Features were studied. Ÿ Parakeratosis Ÿ Hyperkeratosis Ÿ Agranulosis Ÿ Hypergranulosis Ÿ Hypogranulosis Ÿ Suprapapillary Thinning Ÿ Elongation of Rete Ridges Ÿ Micro-munro Abscess Ÿ Kogoj Abscess Ÿ Demal Lymphocytic Infiltrated Ÿ Dilated Blood Vessels Results Ÿ Among 110 cases studied, 91 cases were of Chronic Plaque Psoriasis, 9 Cases were of Guttate Psoriais, 2 cases were of Inverse Psoriais, 3 cases of Erythrodermic Psoriasis, 3 cases of Generalized Pustular Psoriasis and 2 cases of Palmo-plantar Psoriasis. Ÿ Parkeratosis, Hyperkeratosis, Hyogranulosis, Micro-Munro Abscess, Dermal Lymphocytic Infiltrate and Dilated Blood Vessels were prominent Histological findings in this study. Conclusion Ÿ The present study validates that after using combination of varied clinical features and varied histological findings in suspected cases of Psoriasis, we can arrive at the definitive diagnosis of Psoriasis.
Authors and Affiliations
Dr. Vaibhav, Dr. Prabhu M. H, Dr. S. S. Inamdar
Keywords
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