Histopathological study of endometrium in dysfunctional uterine bleeding
Journal Title: International Journal of Medical and Health Research - Year 2018, Vol 4, Issue 12
Abstract
Background: Dysfunctional Uterine Bleeding (DUB) is one of the commonest conditions for which patients seek advice in the gynecological outpatient department. The prevalence increases with age, peaking just prior to menopause. It often occurs when the endometrium, or lining of the uterus, is stimulated to grow by the hormone estrogen. When exposure to estrogen is extended, or not balanced by the presence of progesterone, the endometrium continues to grow until it outgrows its blood supply. Then it sloughs off, causing irregular bleeding. Objective: To evaluate the patterns of endometrial histological findings in women with dysfunctional uterine bleeding and to correlate these findings with clinical features. Material and Methods: Endometrial curettage samples were received and sent to Department of Pathology in 10% formalin and histopathology report were collected. Thorough per speculum and per vaginal examination were done. PAP‟s smear taken and report were collected. Other Hematological, Bio-chemical, Coagulation Profile, Hormonal assay, Thyroid Profile and Radiological investigations were done to analyze DUB cases. Results: The most common endometrial pattern was proliferative endometrium 52% followed by secretory endometrium 18%. The most common menstrual disorder was menorrhagia 75% followed by metorrhagia 14%. DUB was seen maximum 67% in multipara cases followed by 28% in grand multipara. Conclusion: Histopathological examination of endometrium should be done in women presenting with dysfunctional uterine bleeding especially after the age of 40 years to rule out malignancy. Dilatation and curettage reveals endometrial pattern in dysfunctional uterine bleeding in different cases.
Authors and Affiliations
Dr. Kalpana Mehta, Dr. Jitendra Jalandhara, Dr. Ashok Kumawat
Keywords
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