HISTOPATHOLOGICAL STUDY OF SALIVARY GLAND TUMOURS WITH SPECIAL EMPHASIS ON CASES WITH DIAGNOSTIC DILEMMA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 22
Abstract
BACKGROUND Tumours of salivary glands constitute less than 5% of head and neck tumours and are diverse in nature. Some of the tumours pose diagnostic challenge to a pathologist, especially the malignant lesions with poor differentiation. In the present study, we aim to acknowledge the various histological types of salivary gland tumours that we encountered in our institute in a period of 5 years with special emphasis on a few cases posing as a diagnostic dilemma. Aims and Objectives1. To study the histopathological spectrum of salivary gland tumours, identify tumours which pose a diagnostic dilemma and try to classify those tumours with the help of immunohistochemistry. 2. To compare and observe the results of this study with other studies in the contemporary literature. MATERIALS AND METHODS This is a retrospective descriptive study. The source of data is the specimen of salivary glands that were received at Department of Pathology, Indira Gandhi Institute of Medical Sciences, Patna from June 2012 to December 2016. Clinical data and H and E stained slides of sections were retrieved for all the patients undergoing resection of salivary gland tumour during the above mentioned 4.5 years in the hospital. RESULTS A total of 56 cases were diagnosed between June 2012 and 2017. Their ages ranged from 15 years to 85 years. There was a slight male preponderance in both benign and malignant lesions. The most common site was parotid followed by submandibular and minor salivary glands. The most common benign tumour was pleomorphic adenoma followed by Warthin’s tumour, basal cell adenoma and oncocytoma. Among the malignant tumours, the most common was adenoid cystic carcinoma followed closely by mucoepidermoid carcinoma. Immunohistochemistry was needed in five cases to reach a diagnosis. The results were in concordance with other studies done on the subject in India. CONCLUSION Our study aims at studying the various types of salivary gland tumours prevalent in our region and the results conform to other studies done in this field in India.
Authors and Affiliations
Anju Singh, Mona Lisa, Reecha Singh, Kalpana Chandra, Sanjeet Kumar Singh
Keywords
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- EP ID EP433366
- DOI 10.14260/jemds/2018/611
- Views 84
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