Histopathological Study of Spectrum of Ovarian Tumors – A 2 Years Study in a Tertiary Care Institute
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 3
Abstract
Introduction:Ovarian tumours are heterogeneous neoplasms with varied clinical, morphological and histological features. Ovarian tumours account for 3% of cancers in females and is the 5th most common form of cancer related death in females.Epithelial tumors comprise about 60% of all ovarian neoplasms and more than 90% of malignant tumors. Tumors derived from the sex cords or ovarian mesenchyme constitute 5% to 12% of all ovarian neoplasms.Ovarian tumors are often difficult to detect until they are advanced in stage or size, as symptoms are vague and insidious and there is no definite screening programme for early detection. Aims & Objectives:To study the incidence, age distribution and diverse histomorphological spectrum of ovarian tumours. Materials & Methods:This Prospective study of 2 years duration comprised of 116 ovarian neoplasms diagnosed in the department of pathology, in a tertiary care institute. After obtaining clinical data from the records and gross examination, tissue samples from representative area were fixed in formalin, routinely processed, embedded in paraffin and stained with Hematoxylin& Eosin. Tumours were classified according to WHO classification (2014). Histochemistry was done whereverrequired. Results:A total of 116 ovarian neoplasms were studied during this period. Majority were benign tumours (91.4%), followed by malignant (6.9%) and borderline tumours (1.7%). Epithelial tumors comprise about 78.4%, followed by Germ cell tumors (15.5%) and Sex cord-stromal tumors 6%. Serous cystadenoma was the commonest benign tumor and Adult granulosa cell tumour was the commonest malignant ovarian tumour. Conclusion:The prognosis and varying therapeutic strategies of ovarian tumours necessitate an accurate pathological evaluation. Histopathological study is still the gold standard in diagnosing most of these tumours
Authors and Affiliations
Dr. Haritha Bellapu, Dr. B. Anuradha, Dr. B. H. Poorna Chandrasekhar
Keywords
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- EP ID EP555649
- DOI 10.9790/0853-1803082127.
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