Histopathological study of tumours of adipose tissue
Journal Title: INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY - Year 2017, Vol 23, Issue 1
Abstract
Background: Tumours of adipose tissue form one of the largest single groups of soft tissue tumours. The benign, subcutaneous lipoma is the most common soft tissue neoplasm in adults, liposarcoma being the most common primary soft tissue malignancy. Objective: To study the morphological features of the various adipocytic tumours received in the Department of Pathology. Materials and Methods: Cases of adipocytic tumours were retrieved from the archives of the Department of Pathology. Results: The total number of cases numbered 155. Amongst these, 143 (92%) were benign and 12 (8%) were malignant. In benign cases, patients were in the age group 4-75 years, with 88 males and 55 females Among the malignant cases, patients were in the age group 14-68 years, with 7 males and 5 females. The peak age distribution in both benign and malignant cases was in the fourth decade. the most common site of involvement was the nape of neck, followed by back and upper limbs. Conventional lipoma was the most common benign tumour. Variants of lipoma like angiolipoma, chondroid lipoma, dermolipoma etc was noted. Of the 12 malignant tumours, 6 cases were differentiated liposarcoma, 2 cases variant of myxoid liposarcoma and one case each of pleomorphic liposarcoma, lipoleiomyosarcoma and lipoma with sarcomatous changes. Conclusion: Conventional lipomas were the most common adipocytic soft tissue tumours. Malignant cases were rare and among them, the most common malignant tumour was well-differentiated liposarcoma.
Authors and Affiliations
Shilpa Premkumar, Prema Saldanha
Keywords
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