Histopathological study of umbilical cord and placental membranes in clinically suspected cases of chorioamnionitis
Journal Title: Medpulse International Journal of Gynaecology - Year 2018, Vol 8, Issue 2
Abstract
Background: According to the World Health Organization, approximately four million neonates die annually with a global neonatal mortality rate of 23/1,000 live births. About a million of these deaths are attributable to neonatal infections. The placenta is the organ that links mother and foetus during pregnancy. It forms a barrier to toxins and infective organisms. Chorioamnionitis is diagnosed on the basis of either clinical and/or histological findings. Histological chorioamnionitis is the gold standard for defining the maternal and fatal inflammatory responses to microbial organisms in the amniotic fluid. Objective: The aim of the study was to assess the utility of histopathological study of of umbilical cord and placental membranes in clinically suspected cases of chorioamnionitis Material and Methods: This was a prospective study carried out in the Department of OBG, Kodagu institute of medical sciences, Madikeri, from June 2015 to May 2017. All the cases of clinically suspected chorioamnionitis were registered for the study. Histopathological examination of placental membranes and umbilical cord was carried out to detect the presence of histological chorioamnionitis (HCA). Results: In our study HCA was present in 63% and funicitis in 57% of clinically suspected cases of chorioamnionitis. Conclusion: Histopathological examination of umbilical cord and placental membranes is an accurate method to assess the presence of histological chorioamnionitis and neonatal sepsis.
Authors and Affiliations
Somashekar H K, Rashmi B, Manjunatha S
Keywords
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- EP ID EP470468
- DOI 10.26611/1012826
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