HIV-1 Immune evasion: The main obstacle toward a successful vaccine
Journal Title: Archives of Asthma, Allergy and Immunology - Year 2018, Vol 2, Issue 1
Abstract
It is estimated that there are 36.9 million individuals living with HIV-1 from who 21.7 million patients receiving antiretroviral therapy (ART) [1,2]. ART has had a significant effect on the patients’ quality of life recently, however, its global coverage declines to 16-35% in low or middle income parts of Africa [3]. ART is unable to eliminate the virus from the infected individuals despite the fact of great impact on virus life cycle. There is no doubt that vaccination is considered as the most important medical strategy to prevent and suppress the infectious diseases. Nevertheless, there are many difficulties toward the cure or prevention of HIV-1 including the virus characteristics, lack of ideal animal model and funding [4-7].
Authors and Affiliations
MS Larijani, SM Sadat, A Ramezani
Keywords
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- EP ID EP554872
- DOI 10.29328/journal.aaai.1001013
- Views 30
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