HIV/Aids Treatment by Stem Cell Transplantation: A Review
Journal Title: International Journal of Pharmaceutical and Bio-Medical Science - Year 2021, Vol 1, Issue 02
Abstract
Human immunodeficiency virus(HIV)required the presence of CD4 receptor and chemokine receptor (CCR5∆32)to inter into the CD4 host cell. Antiretroviral drugs only blocks the entry of HIV virus into the host cell. The cure of an HIV/AIDS patient the stem cell transplantation from an allogeneic and autologous donor who are homozygous for CCR5∆32receptor mutation has increase research strategies to cure HIV/AIDS to induce long term remission without antiretroviral drugs. Natural CCR5∆32 deficient donors and autologous stem cell transplantation of genetically modified hematopoietic stem cellsare currently under research.This review highlight the previous studies of stem cell transplantationin the treatment of HIV/AIDS.
Authors and Affiliations
Kalpesh Pundlik Mahajan
Keywords
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