Hodgkin’s Lymphoma Occurring Secondary to Autologous Stem Cell Transplantation in Plasma Cell Leukemia; A Case Report
Journal Title: Iranian Journal of Blood and Cancer - Year 2017, Vol 9, Issue 1
Abstract
Survival of patients with multiple myeloma has improved substantially because of availability of new therapies including autotransplants, immunomodulating drugs and proteasome-inhibitors. Second primary cancers have emerged as an important determinant of morbidity and mortality among cancer survivors. Even though there is an increased risk of new cancers of the lymphoreticular and haematopoetic system, it is very rare for Hodgkin’s lymphoma to occur as a second malignancy following autologous peripheral blood stem cell transplantation (APBSCT) for myeloma. We report a case of a female with plasma cell leukemia treated with autologous peripheral blood stem cell transplantation and lenalidamide maintenance. She developed cervical lymphadenopathy 4.5 years after the APBSCT, biopsy confirmed the diagnosis of classical Hodgkin’s lymphoma, nodular sclerosis type. Since she developed allergic reaction to ABVD, she was given 6 cycles of COPP chemotherapy and is in complete remission now.
Authors and Affiliations
Geetha Narayanan, T Manohar Anoop, Lakshmi Haridas, Lali V Soman
Keywords
Related Articles
- EP ID EP240165
- DOI -
- Views 121
- Downloads 0
Determination of Monosomy 7 among In Vitro Generated CD1a Positive Cells in Patients with Juvenile Myelomonocytic Leukemia
Objective: To study whether the generated CD1a positive cells belong to the leukemic cells among patients with juvenile myelomonocytic leukemia. Materials and Methods: We used mononuclear cells from 3 patients with juven...
Zinc Supplementation Effect on Linear Growth in Transfusion Dependent β Thalassemia
Objective: Thalassemic patients are at risk of zinc deficiency due to various causes including desferal injection, hyperzincuria, high ferritin levels, and hepatic iron overload. We evaluate the effect of zinc supplement...
Current Indications of Bone Marrow Transplantation (BMT) in Pediatric Malignant Conditions a Review
Hematopoietic stem cell transplantation (HSCT) has been practiced for more than 30 years. Hematological malignan-cies are the main indications for this treatment. However, its indications in adults are different from ch...
Colorectal and Vulvar Synchronous Cancer: A Case Report
Synchronous cancer is referred to two or more histological distinct malignancies diagnosed during the same hospital admission. Globally more than 1 million people get colorectal cancer yearly resulting in about 0.5 milli...
In-Vitro Red Blood Cells Integrity and Morphology Changes after Passing Through Volumetric Peristaltic Infusion Pump
Background: It is not clear whether the use of volumetric peristaltic infusion pumps, affect the quality of the erythrocytes during packed cell transfusion or not. In the present study in vitro quality of red blood cells...