Hospital Antibiotic Wasting and Evaluation of Potential Ecologic Effects
Journal Title: Annals of Environmental Science and Toxicology - Year 2016, Vol 1, Issue 1
Abstract
Drugs in wastewater arise from direct disposal by healthcare facilities among many other sources. We report the wasting of antibiotics (Ab) dispensed at 2 hospitals in Albany, NY during a 2 year period. We consider drug metabolism, excretion, disposal and toxicity to aquatic organisms in strategies for reducing antibiotic waste and impacts on bacterial resistance. Drug records (12,345) from August, 2008 through April, 2009 included: numbers of drugs dispensed, returned and wasted. Overall, 77 kg of Ab were dispensed but only 1.3 kg were wasted. Six Ab (bacitracin, cefazolin, ceftriaxone, clindamycin, levofloxacin and vancomycin) accounted for 85% (66 kg) of drug dispensed; vancomycin (22 kg) was the most dispensed. Drug wasting as a percent of drug dispensed averaged 1.7% but varied widely. Almost one-half (45%) of the polymyxin B dispensed as a topical ointment was wasted or discarded. Only about 1.6% of vancomycin dispensed was wasted or discarded.
Authors and Affiliations
Mankes Russell F, Silver Charles D
Keywords
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- EP ID EP560431
- DOI 10.17352/pjest.000003
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