Hospitalised patients with Influenza A (H1N1) in the Royal Hospital, Oman Experience of a tertiary care hospital, July–December 2009

Journal Title: Sultan Qaboos University Medical Journal - Year 2010, Vol 10, Issue 3

Abstract

Te aim of this study was to describe the clinical characteristics, risk factors, laboratory investigations and outcome of hospitalised patients with positive Influenza A (H1N1) at the Royal Hospital in Oman. Methods: We extracted data from the retrospective medical charts, radiological and laboratory fndings of 131 patients who were confrmed as positive for Influenza A (H1N1) by real-time reverse-transcriptasepolymerase-chain-reaction from 21 July to 23 December 2009. Results: Te median age was 24 years with 34.4% in the paediatric age group. Most (63%) of hospitalised patients were female. Symptoms at presentation included mainly fever (93.9%) and respiratory symptoms (89.3%). 83% of the patients had at least one risk factor and pregnancy was the most common associated condition (22.9%). Most of the patients had reduced lymphocytic count (57.3%) and high levels of serum C-reactive protein, aspartate transaminase and lactate dehydrogenase (75.7%, 75% and 70.8% respectively). Te majority of the patients (64.5%) had evidence of pneumonia and radiological fndings constituted mainly bi-lateral infltrates (60.6%). Antiviral therapy was administered to 95.4% of the patients who mostly received it 48 hours after disease onset. Death occurred in 6.9% of patients. Out of these, 88.9% required Intensive Care Unit (ICU) care and mechanical ventilation. Conclusion: Influenza A (H1N1) infection mainly affected those of younger age and females. Associated medical conditions were common, with pregnancy being interestingly the commonest risk factor. Te infection caused severe illness that required ICU admission and led to death in 6.9% of patients.

Authors and Affiliations

Jalila Al-Lawati| Department of Microbiology, Royal Hospital, Muscat, Oman, Nada Al-Tamtami| Department of Microbiology, Royal Hospital, Muscat, Oman, Ahmed Al-Qasmi| Department of Epidemiology, Ministry of Health, Muscat, Oman, Amina Al-Jardani| Department of Microbiology, Royal Hospital, Muscat, Oman, Saif Al-Abri| Department of Infectious Diseases, Royal Hospital, Muscat, Oman, Sulaiman Al Busaidy| Central Public Health Laboratory, Ministry of Health, Muscat, Oman

Keywords

Related Articles

Skeletal Muscle Metastasis from Renal Cell Carcinoma 21 cases and review of the literature

Objectives: Tis study aimed to raise radiologists’ awareness of skeletal muscle metastases (SMM) in renal cell carcinoma (RCC) cases and to clarify their imaging appearance. Methods: A retrospective analysis was unde...

A Case of Recurrent Abdominal Pain

The paper decribes the case of a forty-year-old male patient who was admitted with recurrent abdominal pain. Investigations revealed high levels of blood lead; symptoms responded promptly to treatment. The paper also rev...

Measuring Empathy Levels among Kurdish Medical Students in Erbil City, Iraq Cross-sectional study

Objectives: Empathy is a crucial attribute within the physician-patient relationship. Tis study aimed to evaluate the empathy levels of students in the College of Medicine at Hawler Medical University (HMU) in Erbil ci...

Keyhole Surgery of the Kidney at Sultan Qaboos University Hospital, Oman

Objectives: Percutaneous access surgery of the kidneys was introduced in Sultan Qaboos University Hospital (SQUH) in 998. We are presenting our early experience in the first 3 patients operated on over an eight ye...

Download PDF file
  • EP ID EP13972
  • DOI -
  • Views 319
  • Downloads 11

How To Cite

Jalila Al-Lawati, Nada Al-Tamtami, Ahmed Al-Qasmi, Amina Al-Jardani, Saif Al-Abri, Sulaiman Al Busaidy (2010). Hospitalised patients with Influenza A (H1N1) in the Royal Hospital, Oman Experience of a tertiary care hospital, July–December 2009. Sultan Qaboos University Medical Journal, 10(3), 326-334. https://europub.co.uk/articles/-A-13972