How accurate is MRI in prediction of musculoskeletal tumors -A prospective evaluation
Journal Title: International Journal of Biomedical Research - Year 2015, Vol 6, Issue 12
Abstract
Background: To determine the accuracy of MRI in determining the characteristics of musculoskeletal tumors, [including both skeletal (primary/secondary) and soft tissue tumors] and correlation of MRI findings with histopathological study. Methods: 50 consecutive patients referred to the department of radiodiagnosis, of Assam Medical College, Dibrugarh, were included in this study. MRI was performed on 1.5 Tesla superconducting system (MAGNETOM Avanto, Siemens). After localizer sequences, T1W T2W, and STIR images, Fat saturated and post contrast T1W, images were obtained in sagittal, coronal planes, axial planes. Additional sequences like dynamic angiography and spectroscopy were taken when required and when feasible, especially in soft tissue tumors. Results: Features that indicated benignity of soft tissue tumors (under musculo skeletal tumors) are size (< than 6 cm), homogeneity in T2 signal, absence of oedema, necrosis, haemorrhage, fascial penetration, bone changes. Presence of abnormal blood vessels in dynamic angiography, presence of choline peak in spectroscopy was clue to malignancy. A correct histological diagnosis is reached on the basis of imaging studies alone is 66 % of cases. The sensitivity for a MRI diagnosis of bone and soft tissue tumour was 100 % and accuracy was 98 %. Specificity of detecting benignity and malignancy is 94.7%. Conclusion: Diagnosis of musculoskeletal tumors is best made by a combination of clinical and plain picture imaging parameters rather than by any single MR characteristic, except lipomas. When a lesion has a non-specific MR imaging appearance, it is useful to formulate a suitably ordered differential diagnosis based on tumour prevalence, age.
Authors and Affiliations
Mary Hazarika Bhuyan, R K Bhuyan
Prevalence pattern of risk factors for coronary artery disease (CAD) among patients presenting for coronary artery bypass grafting (CABG) in rural Indian population
Objectives: Coronary artery disease (CAD) is the leading cause of death worldwide. The aim of study was to identify the pattern of prevalence of risk factors in CAD patients presenting for surgical revascularization by c...
Comparison of pre-operative and post-operative astigmatism and visual acuity after pterygium excision followed by sutureless and gluefree conjunctival autograft
Objective: To compare change in refractive astigmatism and visual acuity following pterygium excision followed by sutureless and gluefree conjunctival autograft. Method: A prospective , non randomized , comparative and...
Observational Study to Evaluate Transversus Abdominis Plane (TAP) Block in Abdominal Surgery by Total Requirement of Diclofenac as a Post Operative Analgesia drug
Background:Transversus Abdominis Plane Block (TAPB) is a regional anesthesia technique.It provides analgesia after lower abdominal surgery particularly where parietal wall pain forms major component of pain. It allows se...
Financing universal coverage in Kenya A case study
Introduction: One of the challenges to maintain an agenda for universal coverage and equitable health system is to develop effective structuring and management of health financing. Global experiences with different syste...
A Rare case report: Granular cell tumor of the scalp
Granular cell tumor is a soft tissue neoplasm that originates in the nervous system and arises at virtually any body site, but is mainly found in the skin, oral cavity or digestive tract. Most are benign and reportedly m...