HOW TO LIVE WITH RHEUMATOID ARTHRITIS???
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 3
Abstract
Rheumatoid Arthritis (RA) is a chronic auto-immune disease characterized by painful inflammation of the joints and surrounding tissues, leading to long term disability. Rheumatoid arthritis can begin at any age but has its peak between 35 to 55 years of age. RA shows hereditary linkage. Women and smokers are most often affected. The patient doesn’t feel any symptoms during inactive state of the disease. RA progresses in a symmetrical pattern involving both the sides of the body. Once rheumatoid arthritis is confirmed by diagnosis, treatment should start as early as possible. The treatment for rheumatoid arthritis focuses initially on reducing the joint inflammation and pain with the use of analgesics and anti-inflammatory agents. In the next stage, joint function is restored by administering Disease Modifying Anti-rheumatic Drugs (DMARDs) thus preventing joint deformity. Treatment is generally based on the degree of severity of RA. Patients with mild RA are advised to take rest and are prescribed analgesics and anti-inflammatory medicines, which include fast acting drugs like NSAIDs. Slow acting drugs like (DMARDs) such as methotrexate, sulfasalazine, lelflunomide etc., and Body’s reaction modifiers (BRMs) such as rituximab, anankinra, infliximab etc., are reserved for patients suffering from moderate to severe RA. The patient is advised to undertake regular exercises like walking, stretching, swimming or cycling, which are aimed at reducing body weight. The patient suffering from arthritis can carry out his normal day-to-day activities with the help of proper medication and regular exercise.
Authors and Affiliations
Milind Parle , Sushila Kaura
FORMULATION AND EVALUATION OF AMLODIPINE TRANSDERMAL PATCHES USING ETHYL CELLULOSE
The aim of our study was to design and evaluate Amlodipine transdermal patches using polymers such as ethyl cellulose. Matrix type transdermal patches containing Amlodipine were prepared by solvent casting method by usin...
QUALITATIVE PHYTOCHEMICAL SCREENING AND ANTIFUNGAL ACTIVITY OF CARICA PAPAYA LEAF EXTRACT AGAINST HUMAN AND PLANT PATHOGENIC FUNGI
Plants have been explored extensively all over the globe in quest of a novel bioactive compound that could a good therapeutic candidate treating infectious diseases especially against drug resistant microbes. Qualitative...
A NEW OXOTIRUCALLOIC ACID FROM THE STEM BARK OF MANGIFERA INDICA VAR. “LANGRA”
Phytochemical investigation of the ethanolic extract of the stem bark of Mangifera indica variety “Langra” yielded three new phytoconstituents characterized as n-docosan-18′-one-22′-ol-1′-yl hexanoate, 20(R), 24(R)-3-oxo...
TEST OF ANTIOXIDANT ACTIVITY LEAVES OF SCAEVOLA TACCADA (GAERTN.) ROXB. USING DPPH (1, 1-DIPHENYL-2-PICRYLHYDRAZYL)
Free radicals can caused damage cell and tissue which lead to various disease then needed antioxidant as radicals scavenging. The objective of this study was to determine antioxidants activity leaves of Scaevola taccada...
COMPARISON OF DEMINERALIZING EFFECT OF COMMERCIAL EDTA PREPARATIONS AT DIFFERENT TIME INTERVALS BASED ON MEASUREMENT OF THE AMOUNT OF PHOSPHORUS RELEASED FROM HYDROXYAPATITE
The objective of this in-vitro study is to compare the de mineralizing effect of commercial EDTA in different concentrations and different time intervals with respect to the amount of phosphorus released from hydroxyapat...