How to personalize ovarian stimulation in clinical practice
Journal Title: UNKNOWN - Year 2017, Vol 18, Issue 3
Abstract
Controlled ovarian stimulation (COS) in in vitro fertilization (IVF) cycles is the starting point from which couple’s prognosis depends. Individualization in follicle-stimulating hormone (FSH) starting dose and protocol used is based on ovarian response prediction, which depends on ovarian reserve. Anti-Müllerian hormone levels and the antral follicle count are considered the most accurate and reliable markers of ovarian reserve. A literature search was performed for studies that addressed the ability of ovarian reserve markers to predict poor and high ovarian response in assisted reproductive technology cycles. According to the predicted response to ovarian stimulation (poor- normal- or high- response), it is possible to counsel couples before treatment about the prognosis, and also to individualize ovarian stimulation protocols, choosing among GnRH-agonists or antagonists for endogenous FSH suppression, and the FSH starting dose in order to decrease the risk of cycle cancellation and ovarian hyperstimulation syndrome. In this review we discuss how to choose the best COS therapy, based on ovarian reserve markers, in order to enhance chances in IVF.
Authors and Affiliations
Giovanna Sighinolfi, Valentina Grisendi, Antonio La Marca
Keywords
Related Articles
- EP ID EP380024
- DOI 10.4274/jtgga.2017.0058
- Views 60
- Downloads 0
Risk factors for appendiceal involvement in women with epithelial ovarian cancer
Objective: To evaluate the risk factors for appendiceal involvement in women with epithelial ovarian cancer (EOC) who underwent appendectomy at the time of initial surgery. Material and Methods: Patients with a final di...
The assessment of thyroid autoantibody levels in euthyroid patients with polycystic ovary syndrome
Objective: Thyroid hormone abnormalities are commonly seen in polycystic ovary syndrome (PCOS) and have considerable effects on comorbidities. The association with PCOS and thyroid autoimmunity which lead to thyroid path...
Letter from a young female physician, Candidate
.
Prognostic effect of isolated paraaortic nodal spread in endometrial cancer
Objective: To evaluate the prognostic effect of isolated paraaortic lymph node metastasis in endometrial cancer (EC). Material and Methods: This retrospective study included patients with FIGO 2009 stage IIIC2 disease du...
Outcomes of robotic, laparoscopic, and open hysterectomy for benign conditions in obese patients
Objective: To compare outcomes of robotic-assisted (RAH), total laparoscopic hysterectomy (LH), and total abdominal hysterectomy (TAH) for benign conditions in obese patients. Material and Methods: Retrospective cohort (...