hsTropI: an early biomarker of acute coronary syndrome & MI

Journal Title: International Journal of Medical Research and Review - Year 2017, Vol 5, Issue 1

Abstract

In the Emergency Department cardiac troponins are the preferred biomarkers for the diagnosis of acute myocardial infarction (MI) and are useful for risk stratification of patients with acute coronary syndrome (ACS) and stable ischemic heart disease. The introduction of ‘high sensitivity’ Troponins (hscTn) in many tertiary care centers has transformed the diagnostic scenario, wherein, the time from onset of chest pain to its diagnosis has significantly been reduced. With the advent of new hsTnI assays, which have a low limit of detection, low imprecision and low reference limits, the possibility of more patients with unstable angina being classified as having non-ST-elevation myocardial infarction (NSTEMI) will now increase. Its use will identify more high-risk patients with undifferentiated chest pain, that will help ‘rule-in’ or ‘rule-out’ acute myocardial infarction. In conclusion, it may be said that hsTropI is a sensitive, albeit less specific marker of MI. In patients of mildly elevated hsTropI and without evidence of ST elevation, a serial assessment of the biomarker is suggested. This will likely translate into more improved outcomes in this difficult patient population when ECG findings and clinical presentation do not suggest a clear diagnosis.

Authors and Affiliations

Sohini Sengupta Neogi, Raj Kumar Kapoor

Keywords

Related Articles

High field 3T magnetic resonance imaging: MR-anatomy & evaluation of traumatic knee injuries

Background: MRI has high applicability to the knees, in comparison with other joints, and it provides excellent diagnostic capacity for evaluating lesions of different types, such as ligament, meniscal, tendon, bone and...

Pathological findings associated with stillborn babies

Introduction: Fetal death rate and Perinatal Mortality rate are important indicators of a country’s Health care system. Stillbirth forms a prime contributing factor in deciding these rates. But the causes of Stillbirth a...

Distribution of ABO blood groups and Rh(D) factor in and around Anatapuramu, Andhra Pradesh

Background: India is a vast country with lot of diversity in race, religion and creed. The same diversity has been observed in geographical distribution of blood groups in population within country. ABO and Rh blood grou...

Correlation of carotid intimal media thickness with activity and duration of Rheumatoid arthritis using carotid Doppler Ultrasonography

Background: Cardiovascular cause is the leading cause of mortality in RA and this has been attributed to accelerated atherosclerosis. Indirect evidence of accelerated atherosclerosis in RA comes from studies using caroti...

Quality of life in arthritis patients and its correlation with anxiety and depression

Background: Although the medical and economic consequences of arthritis are of great concern to researchers and clinicians, this disease also affects an individual’s capacity to live a full and active life. Aim: To study...

Download PDF file
  • EP ID EP265304
  • DOI 10.17511/ijmrr. 2017.i01.12
  • Views 122
  • Downloads 0

How To Cite

Sohini Sengupta Neogi, Raj Kumar Kapoor (2017). hsTropI: an early biomarker of acute coronary syndrome & MI. International Journal of Medical Research and Review, 5(1), 80-87. https://europub.co.uk/articles/-A-265304