HUMAN RETROVIRUSES AND MODERN CANCER RESEARCH: A REVIEW
Journal Title: World Journal of Pharmaceutical and life sciences - Year 2017, Vol 3, Issue 6
Abstract
The retroviridae family (retroviruses) consists of viruses which require an additional step of reverse transcription during their replication cycle. Cancer and related diseases make up one of the most prevalent causes of mortality. Around 20% of total cancer burden is due to chronic infections and around 15% of cancers are related to viral agents with a higher incidence rate in developing countries. Several human cancers and related malignancies are associated with retroviruses including HIV, breast cancer, prostate cancer and others. Chromosomes in human genome have a number of endogenous retroviral genomes that comprise the human genome. The phylogenetic linkage analysis shows a wide range of oncogenic elements linked to human indigenous retroviruses. They comprise around 1-8% of human genome and follow Mendelian patterns of inheritance. Retroviruses are being employed in newly emerging techniques like gene therapy as delivery vectors. The advanced molecular biology tools and sequencing techniques to analyze retroviruses have opened new horizons in tackling the global cancer burden.
Authors and Affiliations
Zainab Hussain
Keywords
Related Articles
- EP ID EP649190
- DOI -
- Views 199
- Downloads 0
DIVERSITY OF BIRDS IN THE MOIST LOWLAND FOREST OF BUNGUIAO AND DULIAN (UPPER BUNGUIAO), ZAMBOANGA CITY, PHILIPPINES
In the Philippines, nine (9) families of birds are extremely threatened and the Philippine Eagle is one of the critically endangered birds having 400 pairs left in the wild. Anthropogenic activities, like deforestation a...
A LITERARY REVIEW TO UNDERSTAND OVERUSE OF SOCIAL MEDIA AS PRADNYAPARADH
Pradnyaparadha is root of all diseases, according to Ayurveda. Social media is the newest and upcoming epidemic throughout our society, needs a special contemplation because of its increasing prevalence among youth. Basi...
ACCEPTABILITY AND EVALUATION OF IRON RICH CHOCOLATES DEVELOPED USING LOTUS STEM (NELUMBONUCIFERA) AND DATES (PHOENIX DACTYLIFERA) FOR ADOLESCENT GIRLS
According to the World Health Organization (WHO), anemia is defined as hemoglobin levels <12.0 g/dL in women and <13.0 g/dL in men. The frequency and severity of iron deficiency anemia signifies a major health problem. T...
RESPONSE OF GROWTH AND YIELD OF SHALLOTS (ALLIUM ASCOLANICUM L.) BY POTASSIUM NITRATE (KNO3) AND ORGANIC LIQUID FERTILIZATION
The shallots are one of the leading vegetable commodities, but have not shown a real increase in production every year so that efforts are needed to increase the production of shallots. This study aimed to obtain the opt...
NUTRITION AND WOUND CARE
Nutrition is one of the most basic of medical issues and is often ignored as a problem in the management of wound patients. Inadequate dietary intake and poor nutritional status have been identified as key risk factors f...