Humidified high flow nasal cannula oxygen therapy in acute bronchiolitis
Journal Title: Indian Journal of Child Health - Year 2017, Vol 4, Issue 2
Abstract
Background: Bronchiolitis is a major cause of morbidity and leading cause of hospitalization, mostly in early childhood without coexisting illnesses. Traditionally dry oxygen is provided at 100% concentration via low flow nasal prongs. However, the latest studies have revealed that oxygen therapy via heated, humidified, high flow nasal cannula (HFNC) allows the delivery of high inspired gas flows which is better than the traditional one. Methods: All previously healthy children between 1 and 24 months of age with an established clinical diagnosis of moderate to severe bronchiolitis (clinical severity score ≥4) were enrolled for study. The patients were divided into two groups: Patients in Group 1 received HFNC oxygen therapy (HFNC group) while those in Group 2 received conventional oxygen therapy (non-HFNC group). The patients were randomized in each arm by simple randomization. Outcome parameters measured were duration of hospital stay, duration of pediatric intensive care unit (PICU) stay, oxygen saturation (SPO2), respiratory rate, adverse event (respiratory failure), need for intermittent positive pressure ventilation or continuous positive airway pressure. Results: Out of 100 patients studied, 50 received HFNC oxygen and 50 received conventional oxygen. There was early and better improvement in SPO2 and respiratory rate (p<0.001), decreased length of hospital stay (p<0.001) and PICU stay (p<0.01) among the patients in HFNC group as compared to non-HFNC group. The most common adverse event during the hospital course was respiratory failure which was seen among 4 patients in non-HFNC group and none among HFNC group developed such complication. Conclusion: The use of HFNC oxygen therapy in infants hospitalized with acute bronchiolitis reduces PICU and hospital stay as well as the potential complications which will substantially reduce the hospital cost.
Authors and Affiliations
Parvez Ahmed, Javid Maqbool, Mohd Ashraf
Keywords
Related Articles
- EP ID EP454676
- DOI -
- Views 129
- Downloads 0
Opportunistic screening of at risk asymptomatic adolescent children for prediabetes
Background: Type 2 diabetes mellitus (T2DM) once considered an adult disease is now being reported in children and adolescents all over the world due to a parallel increase in obesity. Prediabetes is an intermediate stag...
Assessment of serum sodium levels among the febrile seizures children in a tertiary care hospital
Background: Pathophysiology of febrile seizures (FS) remains unclear. During acute febrile illness, mild disturbances of water and electrolyte balance occur frequently, particularly hyponatremia, which might predispose t...
Macrosomia due to maternal obesity: A case report
Macrosomia, birth weight >4000 g is said to occur in <10% of the pregnancies and is associated with morbidity and mortality in both mother and baby. Although it is more common in diabetic mother, it is also associated wi...
Unwanted penile engorgement in pediatric patients under anesthesia: The role of anesthetic technique and other contributing factors
Background: The mechanism behind intraoperative penile engorgement (PE) is complex. One common myth is that PE occurs more frequently during spinal anesthesia than the general anesthesia. Objective: The objective of this...
Prevalence, clinical profile, and laboratory features of hospitalized under-five children with rotavirus-induced diarrhea
Background: Rotavirus is considered as an important causative agent for pediatric diarrhea. Despite recent studies, data available on the prevalence of diarrhea due to rotavirus, among under-five children, are scarce. Ob...