Hyaluronidase-Sensitive Nanoparticle Templates for Triggered Release of HIV/AIDS Microbicide In Vitro
Journal Title: The AAPS Journal - Year 2014, Vol 16, Issue 2
Abstract
The online version of this article (doi:10.1208/s12248-013-9546-7) contains supplementary material, which is available to authorized users.
Authors and Affiliations
Vivek Agrahari, Chi Zhang, Tao Zhang, Wenjing Li, Todor K. Gounev, Nathan A. Oyler, Bi-Botti C. Youan
Mechanistic Pharmacokinetic/Target Engagement/Pharmacodynamic (PK/TE/PD) Modeling in Deciphering Interplay Between a Monoclonal Antibody and Its Soluble Target in Cynomolgus Monkeys
The online version of this article (doi:10.1208/s12248-013-9545-8) contains supplementary material, which is available to authorized users.
Induction of Death Receptor CD95 and Co-stimulatory Molecules CD80 and CD86 by Meningococcal Capsular Polysaccharide-Loaded Vaccine Nanoparticles
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Quantitative comparison of functional screening by measuring intracellular Ca2+ with radioligand binding at recombinant human dopamine receptors
The purpose of this study was to test whether screening at dopamine receptors performed with a recently described functional assay for G-protein coupled receptors (GPCRs) provides data that correlate significantly with r...
Simulation of Monoclonal Antibody Pharmacokinetics in HumansUsing a Minimal Physiologically Based Model
The online version of this article (doi:10.1208/s12248-014-9640-5) contains supplementary material, which is available to authorized users.
Mechanism-Based Pharmacokinetic Modeling to Evaluate Transporter-Enzyme Interplay in Drug Interactions and Pharmacogenetics of Glyburide
The purpose of this study is to characterize the involvement of hepato-biliary transport and cytochrome-P450 (CYP)-mediated metabolism in the disposition of glyburide and predict its pharmacokinetic variability due to dr...