Hydroalcoholic extracts of three Artemisia species attenuate dental pulp pain and pain-related abnormal feeding behavior of rats
Journal Title: Iranian Journal of Veterinary Science and Technology (IJVST) - Year 2022, Vol 14, Issue 2
Abstract
This study considered the therapeutic efficacy of three different Artemisia species extracts on capsaicin-induced dental pulp pain and pain-associated changes in feeding behaviors in adult male Wistar rats. The animals were alienated into five groups (n=6), comprising: sham, capsaicin, and capsaicin groups pre-treated with hydroalcoholic extracts of A. sieberi, A.persica, and A.biennis. Pulpitis was evoked by intradental administration of capsaicin (100 µg). The plant extracts (200 mg/kg/ i.p.) were administered 10 min before capsaicin. Pain scores were recorded for forty min. Afterward, feeding behavior was evaluated within 6 hours. All extracts could suppress capsaicin-related dental pulp pain. Furthermore, capsaicin decreased the number of visits to the food and water ports of the feeding behavior evaluation device that led to a reduced amount and duration of meals consumed. These harmful effects of capsaicin on meal duration, and frequency were attenuated by A.persica. Moreover, capsaicin inhibitory effect on food intake and water consumption was suppressed by all the extracts. Taken together, the present study showed that Artemisia species extracts are useful in supressing capsaicin-induced pulpal pain and pain-induced feeding abnormalities.
Authors and Affiliations
Jahangir Haghani,Fatemeh Haghani,Amirhosein Soleimani,Mehdi Abbasnejad,Mojteba Khodami,Razieh Kooshki,Maryam Raoof,
Keywords
Related Articles
- EP ID EP722347
- DOI -
- Views 35
- Downloads 0
The current rules on bluetongue vaccination in EU: from the origin to date
The Council Directive 2000/75/EC lays down controlling rules and measures to contrast and to eradicate bluetongue disease, including rules on the establishment of protection and surveillance zones and the use of vaccines...
Prevalence assessment of Salmonella serovars in apparently healthy pet dogs in Tehran, Iran
Salmonellosis is considered to be a zoonotic disease, the transmission of which through oral-fecal contact is unavoidable because pet care has been popular recently. On the other hand, excessive use of human antibiotics...
Antibacterial effect of Satureja hortensis and Salvia officinalis essential oils against major bovine mastitis bacteria
Treatment of bacterial diseases such as bovine mastitis with antibiotics has problems such as antibiotic resistance and drug residue in animal products. Essential oil of medicinal plants have antibacterial activity and...
Ectopic migration of Fasciola sp. in the lung of a water buffalo (Bubalus bubalis)
There are few reports of ectopic fasciolosis in the lungs of ruminants. Here, we report a rare case of ectopic pulmonary migration of Fasciola sp. in a water buffalo (Bubalus bubalis). In October 2021, during the routine...
Effect of Zataria multiflora essential oil on rooster semen during storage at 4°C
Experiment was conducted to determine effect of Zataria multiflora boiss essential oil on stored spermatozoa. Semen collection was performed by using 15 mature roosters twice a week at four times. In each session, ejacul...