Hydrogen Sulfide in Airway Diseases
Journal Title: Pulmonary Research and Respiratory Medicine – Open Journal - Year 2013, Vol 2, Issue 2
Abstract
Hydrogen Sulfide (H2S) is a colorless, water-soluble gas with the odor of rotten eggs. H2S can be produced via non-enzymatic pathways, but is mainly synthesized from L-cysteine as the substrate by Cystathionine-γ-lyase (CSE), Cystathionine-β-synthetase (CBS) and 3-mercaptopyruvate sulfur transferase (3MTS). [1] H2S is now recognized as the third signaling gasotransmitter after Carbon monoxide (CO) and Nitric Oxide (NO), and it plays an important role in the pathophysiology of airway disease, such as asthma and Chronic Obstructive Pulmonary Disease (COPD). [1]
Authors and Affiliations
Feng Li
Keywords
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- EP ID EP550092
- DOI 10.17140/PRRMOJ-2-113
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