Hyperfunctioning Parathyroid Giant Adenoma

Journal Title: Surgical Research – Open Journal - Year 2015, Vol 2, Issue 1

Abstract

Purpose: The objective of this paper is to report the management and treatment of a 47-year-old patient admitted with multiple problems including asthenia, nausea and bradycardia, and was diagnosed with a giant parathyroid adenoma. Case report: A 47-year-old man was admitted to the Department of General Surgery for acute and worsening asthenia, nausea and bradycardia. Blood tests showed hypercalcemia, hypophosporemia, very high serum parathormone level, so that he was diagnosed with primary hyperparathyroidism. Cervical ultrasonography and scintigraphy with technetium 99 mTc Methoxyisobutylisonitrile (99 mTc-MIBI) showed the presence of positive nodule at the isthmus of the thyroid gland. The patient underwent neck exploration. Intra-operative iPTH essay was measured. A giant parathyroid adenoma was identified and excised, with no macroscopic signs of malignancy. Discussion and conclusion: Hyper functioning parathyroid giant adenoma can present with typical symptoms of hypercalcemic crisis: ECG alterations, kidney failure, emotional lability, confusion, delirium, psychosis, asthenia, epilepsy. Elective treatment is the excission. The surgical technique contemplates neck exploration and to ensure the finding of the adenoma, previously identified with imaging tests. It is necessary to measure intra-operative iPTH assay.

Authors and Affiliations

Pasquale Sperlongano

Keywords

Related Articles

Pancreatic Cancer in the Very Elderly Patient: Challenges and Solutions

Pancreatic cancer is responsible for a significant disease burden on the aging US population. The only chance at curing this highly morbid disease is surgical resection, however choosing appropriate surgical candidates i...

The Opportunistic Salpingectomy in Reducing Ovarian Cancer Risk: Do the Potential Benefits Outweigh Complications?

A 33-year-old women with 3 children who has completed child bearing presents to your office for permanent sterilization via a laparoscopic approach. She has recently heard through the internet that removal of the fallopi...

Transverse Colon Perforation in a Patient with Primary Systemic Amyloidosis Associated with Multiple Myeloma

Amyloidosis is caused by extracellular deposits of amyloid by plasma cells, which can be idiopathic, occur with chronic inflammatory conditions, familial, or be associated with Multiple Myeloma. The Gastrointestinal trac...

Lysine Pill-Induced Esophageal Perforation

Pill-induced esophagitis is being increasingly recognized, but remains largely underreported. Most patients suffer from self-limited pain but complications like esophageal hemorrhage, stricture, perforation and even deat...

Surgery in the Era of Molecular Medicine: Review of Gastroenteropanreatic Neuroendocrine Tumours

The management of gastroenteropancreatic neuroendocrine tumours (GEP-NETs) has evolved rapidly in the last two decades. Therefore, it is important that surgeons practicing in molecular medicine era have a clear understan...

Download PDF file
  • EP ID EP558248
  • DOI 10.17140/SROJ-2-108
  • Views 160
  • Downloads 0

How To Cite

Pasquale Sperlongano (2015). Hyperfunctioning Parathyroid Giant Adenoma. Surgical Research – Open Journal, 2(1), 43-46. https://europub.co.uk/articles/-A-558248