Hyperpigmentation of the oral mucosa induced by an antiretroviral drug – a case report
Journal Title: Polski Przegląd Otorynolaryngologiczny - Year 2015, Vol 4, Issue 3
Abstract
Pigmented lesions of the oral cavity are relatively common. They represent a group of clinical entities ranging from physiological changes to manifestations of local or systemic disease. Hyperpigmentation is the result of accumulation of pigment within the tissue. In general, pigmentation of oral tissues may occur due to accumulation of melanin or silver salts. The objective of this paper is to report a case of pigmented oral lesions in a HIV-positive patient treated with zidovudine. The patient is a HIV positive, smoked and took antiretroviral drugs irregularly. Physical examination revealed multiple brown macules in the oral cavity. Biopsy was performed and histopathological examination confirmed the diagnosis of oral melanin hyperpigmentation. This case demonstrates the importance of proper diagnosis and planning for oral pigmented lesions
Authors and Affiliations
Laura Grein Cavalcanti, Rafael Boscheti de Souza, Claudyane de Almeida, Antonio Adilson Soares de Lima
Keywords
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