Hyperprogression after immunotherapy in HNC: literature review and our experience
Journal Title: International Journal of Radiology and Radiation Oncology - Year 2018, Vol 4, Issue 1
Abstract
Checkpoint inhibitors demonstrate salutary anticancer effects, including long-term remissions. PD-L1 expression/amplification, high mutational burden, and mismatch repair deficiency correlate with response. Champiat et al for the first time described a small subset of patients that could actually have tumor growth accelerated when given PD1/PDL1-targeting agents [1].
Authors and Affiliations
Denaro Nerina
Keywords
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- EP ID EP541382
- DOI 10.17352/ijrro.000026
- Views 38
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